Emergence of NDM-1 Metallo-β-Lactamase in Pseudomonas aeruginosa Clinical Isolates from Serbia

被引：154

作者：

Jovcic, Branko ^{[1
]}

Lepsanovic, Zorica ^{[2
]}

Suljagic, Vesna ^{[2
]}

Rackov, Gorjana ^{[2
]}

Begovic, Jelena ^{[1
]}

Topisirovic, Ljubisa ^{[1
]}

Kojic, Milan ^{[1
]}

机构：

[1] Univ Belgrade, Inst Mol Genet & Genet Engn, Belgrade 11010, Serbia

[2] Mil Med Acad, Belgrade 11002, Serbia

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2011年 / 55卷 / 08期

关键词：

ESCHERICHIA-COLI; GENES;

D O I：

10.1128/AAC.00226-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This work reports, for the first time, the presence of New Delhi metallo-beta-lactamase 1 (NDM-1) in Pseudomonas aeruginosa. Moreover, this is the first report of the NDM-1 presence in the Balkan region. Cosmid gene libraries of carbapenem-nonsusceptible Pseudomonas aeruginosa clinical isolates MMA83 and MMA533 were screened for the presence of metallo-beta-lactamases. Accordingly, both MMA83 and MMA533 carried the bla(NDM-1) gene. Pulsed-field gel electrophoresis (PFGE) analysis indicated that strains MMA83 and MMA533 belonged to different clonal groups. Five additional isolates from different patients clonally related to either MMA83 or MMA533 were found to be NDM-1 positive.

引用

页码：3929 / 3931

页数：3

共 50 条

[1] Inhibition studies on metallo-β-lactamase NDM-1
Treon, Margaret
Yang, Hao
Crowder, Michael W.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 247
[2] Spectroscopic and mechanistic studies on metallo-β-lactamase NDM-1
Yang, Hao
Aitha, Mahesh
Hetrick, Alyssa
Bennett, Brian
Tierney, David L.
Sutton, Larry
Crowder, Michael W.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246
[3] New Delhi Metallo-β-Lactamase (NDM-1): An Update
Shakil, S.
Azhar, E. I.
Tabrez, S.
Kamal, M. A.
Jabir, N. R.
Abuzenadah, A. M.
Damanhouri, G. A.
Alam, Q.
JOURNAL OF CHEMOTHERAPY, 2011, 23 (05) : 263 - 265
[4] Mechanistic and Spectroscopic Studies of Metallo-β-lactamase NDM-1
Yang, Hao
Aitha, Mahesh
Hetrick, Alyssa M.
Richmond, Timothy K.
Tierney, David L.
Crowder, Michael W.
BIOCHEMISTRY, 2012, 51 (18) : 3839 - 3847
[5] Emergence of VIM-2 metallo-β-lactamase-producing Pseudomonas aeruginosa isolates in a paediatric hospital in Serbia
Jovcic, Branko
Vasiljevic, Zorica
Djukic, Slobodanka
Topisirovic, Ljubisa
Kojic, Milan
JOURNAL OF MEDICAL MICROBIOLOGY, 2011, 60 (06) : 868 - 869
[6] Two copies of bla NDM-1 gene are present in NDM-1 producing Pseudomonas aeruginosa isolates from Serbia
Jovcic, Branko
Lepsanovic, Zorica
Begovic, Jelena
Filipic, Brankica
Kojic, Milan
ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY, 2014, 105 (03): : 613 - 618
[7] Structure of New Delhi metallo-β-lactamase 1 (NDM-1)
Green, Victoria L.
Verma, Anil
Owens, Raymond J.
Phillips, Simon E. V.
Carr, Stephen B.
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 2011, 67 : 1160 - 1164
[8] Discovery of thiosemicarbazone derivatives as effective New Delhi metallo-β-lactamase-1(NDM-1) inhibitors against NDM-1 producing clinical isolates
Bing Zhao
Xinhui Zhang
Tingting Yu
Ying Liu
Xiaoling Zhang
Yongfang Yao
Xuejian Feng
Hongmin Liu
Dequan Yu
Liying Ma
Shangshang Qin
ActaPharmaceuticaSinicaB, 2021, 11 (01) : 203 - 221
[9] Discovery of thiosemicarbazone derivatives as effective New Delhi metallo-β-lactamase-1 (NDM-1) inhibitors against NDM-1 producing clinical isolates
Zhao, Bing
Zhang, Xinhui
Yu, Tingting
Liu, Ying
Zhang, Xiaoling
Yao, Yongfang
Feng, Xuejian
Liu, Hongmin
Yu, Dequan
Ma, Liying
Qin, Shangshang
ACTA PHARMACEUTICA SINICA B, 2021, 11 (01) : 203 - 221
[10] Clinical Isolates of Salmonella enterica Serovar Agona Producing NDM-1 Metallo-β-Lactamase: First Report from Pakistan
Irfan, Seema
Khan, Erum
Jabeen, Kauser
Bhawan, Pushpa
Hopkins, Katie L.
Day, Martin
Nasir, Amna
Meunier, Daniele
Woodford, Neil
JOURNAL OF CLINICAL MICROBIOLOGY, 2015, 53 (01) : 346 - 348

← 1 2 3 4 5 →