Coenzyme Q10 deficiency in septic shock patients

被引：7
|
作者：
Dupic, Laurent [2 ]
Huet, Olivier [1 ,3 ]
Duranteau, Jacques [1 ]
机构：
[1] Univ Paris 11, Hop Bicetre, AP HP, Dept Anesthesie Reanimat,EA 3509, F-94275 Le Kremlin Bicetre, France
[2] Univ Paris 05, Hop Necker Enfants Malad, AP HP, F-75015 Paris, France
[3] BakerIDI Heart & Diabet Inst, Vasc Pharmacol Lab, Melbourne, Vic 3004, Australia
来源：
CRITICAL CARE | 2011年 / 15卷 / 05期
关键词：
SEPSIS;
D O I：
10.1186/cc10429
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Donnino and colleagues provide new insights into the field of oxidative stress and mitochondrial dysfunction during septic shock. These authors suggest a coenzyme Q(10) (CoQ(10)) deficiency in patients with septic shock. Larger prospective observational trials measuring CoQ(10) in patients with septic shock are required to confirm the possibility of CoQ(10) depletion. This study is a new step toward a study testing CoQ(10) as a potential therapeutic agent for patients with septic shock.
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页数：2
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