High hydrostatic pressure (HHP) inactivation of five pharmacopoeia strains including spores of Bacillus subtilis

被引:0
|
作者
Rigaldie, Y [1 ]
Largeteau, A [1 ]
Lemagnen, G [1 ]
Grislain, L [1 ]
Demazeau, G [1 ]
机构
[1] ENSCPB, LPCHP, Lab Physicochim Hautes Press, Interface Rech ICMCB, F-33608 Pessac, France
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中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In order to evaluate the high pressure capability to inactivate micro-organisms for pharmaceutical applications (decontamination and sterilization of fragile drugs), we have developed high pressure treatments for strains inactivation in agreement with the European Pharmacopoeia requirements.
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页码:283 / 286
页数:4
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