Gold(I)-Catalyzed Cascade for Synthesis of Pyrrolo[1,2-a:2′,1′-c]-/Pyrido[2,1-c]pyrrolo[1,2-a]quinoxalinones

被引：32
|
作者：
Zhou, Yu [1 ]
Ji, Xun [1 ,2 ]
Liu, Guannan [1 ]
Zhang, Dengyou [1 ]
Zhao, Linxiang [2 ]
Jiang, Hualiang [1 ]
Liu, Hong [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
[2] Shenyang Pharmaceut Univ, Sch Pharmaceut Engn, Shenyang 110016, Liaoning, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2010年 / 352卷 / 10期
基金：
中国国家自然科学基金;
关键词：
alkynes; aromatic amines; cascade reactions; gold catalysts; pyrrolo[1,2-a:2 ',1 '-c]-/pyrido[2,1-c]pyrrolo[1,2-a]quinoxalinones; CATALYZED TANDEM SYNTHESIS; GOLD CATALYSIS; INTRAMOLECULAR CYCLIZATION; STEREOCENTERS; EFFICIENT;
D O I：
10.1002/adsc.201000199
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
An efficient and convenient method was developed for the one-pot construction of the complex polycyclic heterocycles pyrrolo[1,2-a:2',1'-c]-/pyrido[2,1-c]pyrrolo[1,2-a]quinoxalinones from two simple starting materials via a gold(I)-catalyzed domino reaction. This strategy presents an atom economical and environmentally friendly transformation, in which two new C-N bonds and one new C-C bond are formed in a one-pot reaction process.
引用
收藏
页码：1711 / 1717
页数：7
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