Prospective evaluation of plasma cortisol in recent trauma survivors with posttraumatic stress disorder

被引：49

作者：

Bonne, O

Brandes, D

Segman, R

Pitman, RK

Yehuda, R

Shalev, AY

机构：

[1] Hadassah Univ Hosp, Ctr Traumat Stress, IL-91120 Jerusalem, Israel

[2] Harvard Univ, Sch Med, Boston, MA USA

[3] Massachusetts Gen Hosp, Boston, MA 02114 USA

[4] Mt Sinai Sch Med, Dept Psychiat, New York, NY USA

[5] Dept Vet Affairs Med Ctr, Dept Psychiat, Posttraumat Stress Disorder Program, Bronx, NY 10468 USA

来源：

PSYCHIATRY RESEARCH | 2003年 / 119卷 / 1-2期

关键词：

hypothalamic-pituitary-adrenal axis; prognosis; longitudinal;

D O I：

10.1016/S0165-1781(03)00098-2

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Hypothalamic pituitary adrenal axis abnormalities have been described in posttraumatic stress disorder (PTSD), and among the recently traumatized. Plasma cortisol and continuous measures of PTSD symptoms were obtained from 21 survivors, at 1 week and 6 months after traumatic events. Eight survivors met Clinician Administered PTSD Scale criteria for PTSD at 6 months. Cortisol levels at 1 week did not predict subsequent PTSD. Survivors with and without PTSD had similar mean levels of cortisol at both time points. Cortisol levels at 6 months negatively correlated with self-reported PTSD symptoms within PTSD subjects. (C) 2003 Elsevier Ireland Ltd. All rights reserved.

引用

页码：171 / 175

页数：5

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