Asymmetric reduction of ketones with recombinant E. coli whole cells in neat substrates

被引：90

作者：

Jakoblinnert, Andre ^{[2
]}

Mladenov, Radoslav ^{[2
]}

Paul, Albert ^{[2
]}

Sibilla, Fabrizio ^{[2
]}

Schwaneberg, Ulrich ^{[2
]}

Ansorge-Schumacher, Marion B. ^{[3
]}

de Maria, Pablo Dominguez ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, ITMC, D-52074 Aachen, Germany

[2] Rhein Westfal TH Aachen, Lehrstuhl Biotechnol, D-52074 Aachen, Germany

[3] Tech Univ Berlin, Inst Chem, Dept Enzyme Technol TC4, D-10623 Berlin, Germany

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 44期

关键词：

SECONDARY ALCOHOL-DEHYDROGENASE; BAKERS-YEAST; CANDIDA-PARAPSILOSIS; KINETIC RESOLUTION; ENZYMES; BIOTRANSFORMATION; MEDIA; WATER;

D O I：

10.1039/c1cc14097c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The asymmetric reduction of ketones is performed by using lyophilized whole cells in neat substrates with defined water activity (a(w)). Ketones and alcohols prone to be unstable in aqueous media can now be converted via biocatalysis.

引用

页码：12230 / 12232

页数：3

共 50 条

[1] Highly enantioselective reduction of ketones with recombinant E-coli cells
Ema, Tadashi
Okita, Nobuyasu
Takeda, Masahiro
Korenaga, Toshinobu
Sakai, Takashi
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2007, 48 (3-4) : 112 - 112
[2] Asymmetric reduction of ketones using recombinant E-coli, cells that produce a versatile carbonyl reductase with high enantioselectivity and broad substrate specificity
Ema, Tadashi
Yagasaki, Hideo
Okita, Nobuyasu
Takeda, Masahiro
Sakai, Takashi
TETRAHEDRON, 2006, 62 (26) : 6143 - 6149
[3] Efficient biocatalytic stereoselective reduction of methyl acetoacetate catalyzed by whole cells of engineered E. coli
Cui, Y. H.
Wei, P.
Peng, F.
Zong, M. H.
Lou, W. Y.
RSC ADVANCES, 2018, 8 (18) : 9970 - 9978
[4] Immobilization of recombinant E. coli cells with phenol-lyase activity
Bielecki, S
Bolek, R
IMMOBILIZED CELLS: BASICS AND APPLICATIONS, 1996, 11 : 472 - 478
[5] Mossbauer studies of the transcription factor FNR in whole cells of E. coli
Münck, E
Popescu, C
Bates, D
Beinert, H
Kiley, PJ
JOURNAL OF INORGANIC BIOCHEMISTRY, 1999, 74 (1-4) : 42 - 42
[6] A recombinant E. coli bioprocess for hyaluronan synthesis
Mao, Zichao
Shin, Hyun-Dong
Chen, Rachel
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2009, 84 (01) : 63 - 69
[7] Expression of recombinant mouse spastin in E. coli
Wang, Yujuan
2020 INTERNATIONAL CONFERENCE ON ENERGY, ENVIRONMENT AND BIOENGINEERING (ICEEB 2020), 2020, 185
[8] A recombinant E. coli bioprocess for hyaluronan synthesis
Zichao Mao
Hyun-Dong Shin
Rachel Chen
Applied Microbiology and Biotechnology, 2009, 84 : 63 - 69
[9] Secretion of recombinant proteins from E. coli
Kleiner-Grote, Gabriele R. M.
Risse, Joe M.
Friehs, Karl
ENGINEERING IN LIFE SCIENCES, 2018, 18 (08): : 532 - 550
[10] Synthesis of Optically Active Amines Employing Recombinant ω-Transaminases in E. coli Cells
Koszelewski, Dominik
Goeritzer, Madeleine
Clay, Dorina
Seisser, Birgit
Kroutil, Wolfgang
CHEMCATCHEM, 2010, 2 (01) : 73 - 77

← 1 2 3 4 5 →