Hepatitis B Immunoglobulin Immunoprophylaxis for Hepatitis B: High, Low, or No Dose?

被引：3
|
作者：
Gane, Ed [1 ]
机构：
[1] Auckland City Hosp, New Zealand Liver Transplant Unit, Auckland 1001, New Zealand
来源：
LIVER TRANSPLANTATION | 2010年 / 16卷
关键词：
LIVER-TRANSPLANT RECIPIENTS; RECEIVING LAMIVUDINE PROPHYLAXIS; ADEFOVIR DIPIVOXIL; VIRUS RECURRENCE; PASSIVE IMMUNOPROPHYLAXIS; COMBINATION; PREVENTION; PLUS; IMMUNIZATION; VACCINATION;
D O I：
10.1002/lt.22151
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Key Points 1. Transplantation for HBV-related HCC is increasing in the West, whilst HBV-relate liver failure is decreasing. 2. Combination lamivudine plus HBIG reduces the risk of HBV recurrence to less than 5%. 3. Low-dose IM HBIG ihas similar efficacy and better cost effectiveness than high-dose IV HBIG when combined with oral nucleos(t)ide therapy. 4. HBIG may be discontinued in low risk recipients (undetectable HBV DNA prior to transplant). 5. Combination of new potent antivirals without cross resistance may minimise the future need for post-operative HBIG. Liver Transpl 16:S36-S39, 2010. copy; 2009 AASLD. Copyright © 2009 American Association for the Study of Liver Diseases.
引用
收藏
页码：S36 / S39
页数：4
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