SYNTHESIS AND BIOEFFICACY TEST OF SOME NOVEL HALOGENATED-4-[(SUBSTITUTED-BENZOTHIAZOL-2-YL)-HYDRAZONO]-2-(SUBSTITUTED PHENYL)-5-METHYL-2, 4-DIHYDRO-PYRAZOL-3-ONE

被引：6
|
作者：
Sareen, V. [1 ]
Khatri, V. [1 ]
Sharma, K. [1 ]
Shinde, D. [1 ]
Sareen, S. [1 ]
机构：
[1] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India
来源：
HETEROCYCLIC COMMUNICATIONS | 2010年 / 16卷 / 01期
关键词：
DERIVATIVES;
D O I：
10.1515/HC.2010.16.1.39
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Some new 4-[(substituted-benzothiazol-2-yl)-hydrazono]-2-(substituted phenyl) -5-methyl- 2, 4-dihydro-pyrazol-3-one (3) have been prepared by reacting substituted benzothiazol-2-yl amine with acetoacetic ester, 2-[substituted benzothiazol -2-yl)-hydrazono]-3-oxo-butyric acid ethyl ester (2) react with different hydrazines to give the title compounds. These compounds are evaluated for their antimicrobial activity. The structures of all these compounds have been confirmed by I.R., (1)HNMR,Mass spectra and elemental analysis data.
引用
收藏
页码：39 / 42
页数：4
相关论文
共 50 条
  • [1] SYNTHESIS, CHARACTERIZATION AND BIOCIDAL ACTIVITY OF NOVEL HALOGENATED - 4-[(SUBSTITUTED-BENZOTHIAZOL-2-YL)HYDRAZONO]-2(SUBSTITUTED-PHENYL)-5-METHYL /ETHOXY -2,4-DIHYDRO-PYRAZOL-3-ONE DERIVATIVES
    Khatri, V.
    Sharma, K.
    Sareen, V.
    Shinde, D.
    Sareen, S.
    HETEROCYCLIC LETTERS, 2012, 2 (02): : 174 - 180
  • [2] SYNTHESIS AND CHARACTERIZATION OF SOME NOVEL 4-[(SUBSTITUTED BENZOTHIAZOL-2-YL) HYDRAZONO]-3-METHYL-5-(SUBSTITUTED PHENYL IMINO)-4, 5-DIHYDROISOXAZOLE
    Sareen, S.
    Khatri, V.
    Sareen, V.
    HETEROCYCLIC LETTERS, 2015, 5 (01): : 137 - 141
  • [3] SYNTHESIS OF 4-[(SUBSTITUTED-BENZOTHIAZOL-2-YL)-HYDRAZONO]-3-METHYL/ETHOXY-4H-ISOXAZOL-5-ONES AND THEIR ANTIMICROBIAL ACTIVITY
    Sareen, V.
    Khatri, V.
    Shinde, D.
    Sareen, S.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2011, 21 (01) : 73 - 76
  • [4] Synthesis of some novel (1-substituted-5-phenyl-3-trifluoromethyl-1H-pyrazol-4-yl)-(substituted benzothiazol-2-yl)-diazene and their antifungal activity
    Sareen, V.
    Khatri, V.
    Shinde, D.
    Sareen, S.
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2010, 87 (11) : 1415 - 1419
  • [5] Novel 5-Methyl-2-[(un)substituted phenyl]-4-{4,5-dihydro-3-[(un)substituted phenyl]-5-(1,2,3,4-tetrahydroisoquinoline-2-yl)pyrazol-1-yl}-oxazole Derivatives: Synthesis and Anticancer Activity
    Liu Xinhua
    Bai Linshan
    Pan Chunxiu
    Song Baoan
    Zhu Hailiang
    CHINESE JOURNAL OF CHEMISTRY, 2009, 27 (10) : 1957 - 1961
  • [6] Novel 3-(2-(3-methyl-5-substituted-phenyl-4,5-dihydropyrazol-1-yl)-2-oxoethoxy)-2-substituted-phenyl-4H-chromen-4-one: Synthesis and Anticancer Activity
    Liu, Xin-Hua
    Li, Jun
    Wu, Fan-Rong
    Song, Bao-An
    Bhadury, Pinaki S.
    Shi, Lei
    MEDICINAL CHEMISTRY, 2011, 7 (06) : 605 - 610
  • [7] Synthesis and Antimicrobial Activities of Novel Series of 3-(4-(2-substituted thiazol-4-yl)phenyl)-2-(4-methyl-2-substituted thiazol-5-yl) thiazolidin-4-one Derivatives
    Shelke, Shivaji H.
    Mhaske, Pravin C.
    Narkhade, Sachin
    Bobade, Vivek D.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2014, 51 (04) : 1151 - 1156
  • [8] SYNTHESIS OF SOME 2-(3',5'-DIMETHYLPYRAZOL-1'-YL)-4-METHYL-6-SUBSTITUTED-QUINOLINES AND THEIR 4'-SUBSTITUTED ANALOGS
    SINGH, SP
    VAID, RK
    PRAKASH, I
    PRAKASH, O
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1986, 25 (09): : 945 - 950
  • [9] Synthesis of new 2-(substituted)-5-methyl-2,3-dihydro-1,3,2 λ5 -benzoxazaphosphol-2-ones
    Venkateswarlu, C.
    Satynarayana, P. V. V.
    Rao, C. V. Nageswara
    Raju, C. Naga
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2012, 51 (03): : 521 - 524
  • [10] Efficient Multicomponent Synthesis of Methyl 2-(Benzyloxy)-5-[2-(2-{[3-(substituted phenyl)-1-phenyl-1H-pyrazol-4-yl]­methylidene}hydrazinyl)-1,3-thiazol-4-yl]benzoates
    V. R. Bhosale
    V. S. Kapase
    Russian Journal of Organic Chemistry, 2025, 61 (1) : 105 - 110
12345