Triethylamine Promoted the C-C Bond Cleavage of α-Halo Ketones: α-Acetoxyaryl Ketone Synthesis

被引：4

作者：

Wang, Maorui ^{[1
]}

Wu, Yuzheng ^{[1
]}

Yao, Jian ^{[1
]}

Deng, Li ^{[1
]}

Pan, Yingming ^{[1
]}

Huang, Kebin ^{[1
]}

Tang, Haitao ^{[1
]}

机构：

[1] Guangxi Normal Univ, Sch Chem & Pharmaceut Sci, State Key Lab Chem & Mol Engn Med Resources, Guilin 541004, Guangxi, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 39卷 / 11期

基金：

中国国家自然科学基金;

关键词：

cleavage of C-C bonds; alpha-halo ketones; oxidant-free and metal-free; alpha-acetoxyaryl ketone; CARBOXYLIC-ACIDS; ALKYL ARYL; SELECTIVE OXIDATION; MOLECULAR-OXYGEN; VISIBLE-LIGHT; LIGNIN MODELS; METAL; EFFICIENT; IODINE; FUNCTIONALIZATION;

D O I：

10.6023/cjoc201904051

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The cleavage of C-C bonds is a key method for synthesis of useful intermediates. A novel amine-promoted C-C bond cleavage of alpha-halo ketones was reported. Oxidant-free and metal-free conditions are the striking features of the protocol. In this simple method, a variety of alpha-acetoxyaryl ketone compounds were prepared from commercially available alpha-halo ketones in good to excellent yields.

引用

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页码：3223 / 3229

页数：7

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