Propofol/remifentanil versus sevoflurane/remifentanil in paediatric anaesthesia

被引:21
|
作者
Schmidt, J
Fechner, J
Fritsch, B
Schmitz, B
Carbon, R
Rösch, W
Albrecht, S
机构
[1] Univ Erlangen Nurnberg, Anasthesiol Klin, D-91054 Erlangen, Germany
[2] Univ Erlangen Nurnberg, Chirurg Klin & Poliklin, D-8520 Erlangen, Germany
[3] Univ Erlangen Nurnberg, Urol Klin Poliklin, D-8520 Erlangen, Germany
来源
ANAESTHESIST | 2001年 / 50卷 / 10期
关键词
paediatric anaesthesia; remifentanil; sevoflurane; propofol; recovery times; postoperative comfort;
D O I
10.1007/s001010100207
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Introduction. The aim of this study was to compare total intravenous anaesthesia (TIVA) using propofol and remifentanil (P/R-group) and balanced anaesthesia (BA) using sevoflurane and remifentanil (S/R-group) for paediatric surgery. Patients and methods. A total of 120 patients aged 6 months to 16 years scheduled for elective minor lower abdominal surgery were randomly assigned to receive either propofol (5-10 mg/kg/h) and remifentanil (0.125-1.0 mug/kg/min) or sevoflurane (1.0-1.5 MAC) and remifentanil (0.125-1.0 mug/kg/min). Perioperative haemodynamics as well as recovery and discharge times, PONV and side-effects were studied. The patients vigilance, comfort and pain intensity were assessed postoperatively using the objective pain discomfort scale, the Steward post-anaesthetic recovery score and a visual analogue scale. Results. Postoperative recovery (9.0 vs 11.6 min) and extubation times (11.8 vs. 15.0 min) as well as the time taken until a Steward post-anaesthetic recovery score >3/4 (15.2 vs.21.4 min) was reached were significantly shorter in the P/R-group. However, the length of time until discharge to the ward, postoperative comfort, pain intensity and analgesic requirements as well as PONV were comparable in both groups. Conclusions. With regards to the investigated parameters,TIVA with propofol and remifentanil is equally effective as BA with sevoflurane and remifentanil in paediatric patients. However, considering the selected dosing regimen, recovery times were significantly shorter for children after TIVA.
引用
收藏
页码:757 / 766
页数:10
相关论文
共 50 条
  • [1] Propofol/remifentanil vs sevoflurane/remifentanil for maintenance of anaesthesia during craniotomy
    Tsubokawa, T
    Andrews, CJ
    Sneyd, JR
    [J]. ANESTHESIOLOGY, 2000, 93 (3A) : U152 - U152
  • [2] Comparison of propofol/remifentanil and sevoflurane/remifentanil for maintenance of anaesthesia for elective intracranial surgery
    Sneyd, JR
    Andrews, CJH
    Tsubokawa, T
    [J]. BRITISH JOURNAL OF ANAESTHESIA, 2005, 94 (06) : 778 - 783
  • [3] Remifentanil/propofol versus remifentanil/sevoflurane anesthesia in neurosurgery: A prospective randomized trial
    Blumrich, W
    Meyer, K
    Hans, FJ
    Priebe, HJ
    [J]. ANESTHESIOLOGY, 1997, 87 (03) : A149 - A149
  • [4] Sevoflurane/remifentanil versus propofol/remifentanil for electroconvulsive therapy: Comparison of seizure duration and haemodynamic responses
    Ulusoy, Hulya
    Cekic, Bahanur
    Besir, Ahmet
    Geze, Sukran
    Hocaoglu, Cicek
    Akdogan, Ali
    [J]. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2014, 42 (01) : 111 - 119
  • [5] Bronchial mucus transport velocity in patients receiving propofol and remifentanil versus sevoflurane and remifentanil anesthesia
    Ledowski, T
    Paech, MJ
    Patel, B
    Schug, SA
    [J]. ANESTHESIA AND ANALGESIA, 2006, 102 (05): : 1427 - 1430
  • [6] Haemodynamic effects of anaesthesia induction with etomidate/remifentanil followed by sevoflurane/remifentanil balanced anaesthesia
    Klaric, M.
    Diers, A.
    Klingler, H.
    Bantel, C.
    Weyland, A.
    [J]. ANASTHESIOLOGIE & INTENSIVMEDIZIN, 2021, 62 : 474 - 485
  • [7] Propofol versus remifentanil for monitored anaesthesia care during colonoscopy
    Moerman, AT
    Foubert, LA
    Herregods, LL
    Struys, MMRF
    De Wolf, DJ
    De Looze, DA
    De Vos, MM
    Mortier, EP
    [J]. EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2003, 20 (06) : 461 - 466
  • [8] Comparison of the antitussive effect of remifentanil during recovery from propofol and sevoflurane anaesthesia
    Kim, H.
    Choi, S. -H.
    Choi, Y. -S.
    Lee, J. -H.
    Kim, N. -O.
    Lee, J. -R.
    [J]. ANAESTHESIA, 2012, 67 (07) : 765 - 770
  • [9] TIVA with propofol/remifentanil compared to balanced anaesthesia with sevoflurane/fentanyl in gynaecological laparoscopic surgery
    Juckenhöfel, S
    Feisel, C
    Schmitt, HJ
    Biedler, A
    [J]. ANAESTHESIST, 1999, 48 (11): : 807 - 812
  • [10] Mastocytosis: general anaesthesia with remifentanil and sevoflurane.
    Auvray, L
    Letourneau, B
    Freysz, M
    [J]. ANNALES FRANCAISES D ANESTHESIE ET DE REANIMATION, 2001, 20 (07): : 635 - 638