One-Pot Synthesis of Decahydropyrene via Tandem C-H Activation/Intramolecular Diels-Alder/1,3-Dipolar Cycloaddition

被引：13
|
作者：
Lin, Hui [1 ]
Dong, Lin [1 ]
机构：
[1] Sichuan Univ, West China Sch Pharm, Educ Minist, Key Lab Drug Targeting & Drug Delivery Syst, Chengdu 610041, Peoples R China
来源：
ORGANIC LETTERS | 2016年 / 18卷 / 21期
关键词：
INTERNAL ALKYNES; POLYHETEROAROMATIC COMPOUNDS; CATALYZED ANNULATION; CARBOXYLIC-ACIDS; DIRECTING GROUPS; BOND ACTIVATION; N-OXIDES; HYDROGENATION; BENZAMIDES; ARYLATION;
D O I：
10.1021/acs.orglett.6b02768
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel decahydropyrene synthesis has been successfully developed involving a tandem rhodium-catalyzed C-H activation/intramolecular Diels-Alder reaction/1,3-dipolar cycloaddition cascade process by using diazole as a traceless directing group. The advantage of this one-pot strategy is a quite simple, efficient, highly stereoselective, and unique product structure.
引用
收藏
页码：5524 / 5527
页数：4
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