Ruthenium-Catalyzed Regio- and Stereoselective Addition of Carboxylic Acids to Aryl and Trifluoromethyl Group Substituted Unsymmetrical Internal Alkynes

被引：63
|
作者：
Kawatsura, Motoi [1 ]
Namioka, Junya [1 ]
Kajita, Koji [1 ]
Yamamoto, Mitsuaki [1 ]
Tsuji, Hiroaki [1 ]
Itoh, Toshiyuki [1 ]
机构：
[1] Tottori Univ, Grad Sch Engn, Dept Chem & Biotechnol, Tottori 6808552, Japan
来源：
ORGANIC LETTERS | 2011年 / 13卷 / 12期
关键词：
MARKOVNIKOV TRANS-ADDITION; ENOL-ESTER SYNTHESIS; TERMINAL ALKYNES; VINYLIDENE COMPLEXES; DIMERIZATION; BOND;
D O I：
10.1021/ol201238u
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The regio- and stereoselective addition of carboxylic acids to aryl and trifluoromethyl group substituted unsymmetrical Internal alkynes has been accomplished: the Ru-3(CO)(12)/3PPh(3) catalyst system has effectively catalyzed the reaction to afford the trifluoromethyl group substituted (E)-enol esters with high regio- and stereoselectivities.
引用
收藏
页码：3285 / 3287
页数：3
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