Controlled Evaluation of the Effects of Hyperbaric Oxygen Therapy on the Behavior of 16 Children with Autism Spectrum Disorders

被引：25

作者：

Jepson, Bryan ^{[1
]}

Granpeesheh, Doreen ^{[2
]}

Tarbox, Jonathan ^{[2
]}

Olive, Melissa L. ^{[2
]}

Stott, Carol ^{[1
]}

Braud, Scott ^{[2
,3
]}

Yoo, J. Helen ^{[2
]}

Wakefield, Andrew ^{[1
]}

Allen, Michael S. ^{[2
,4
]}

机构：

[1] Thoughtful House Ctr Children, Austin, TX USA

[2] Ctr Autism & Related Disorders Inc, Tarzana, CA 91356 USA

[3] HOPE Reach, Holland, MI USA

[4] Connecticut Behav Heath, Middletown, CT USA

来源：

JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS | 2011年 / 41卷 / 05期

关键词：

Hyperbaric oxygen therapy; Autism; Behavioral pharmacology; ACUTE ISCHEMIC-STROKE; DEVELOPMENTAL-DISABILITIES; FUNCTIONAL-ANALYSIS; REGRESSIVE AUTISM; CEREBRAL-PALSY; ANIMAL-MODEL; BRAIN; NEUROINFLAMMATION; INFLAMMATION; ACTIVATION;

D O I：

10.1007/s10803-010-1075-y

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Hyperbaric oxygen therapy (HBOT) has been used to treat individuals with autism. However, few studies of its effectiveness have been completed. The current study examined the effects of 40 HBOT sessions at 24% oxygen at 1.3 ATA on 11 topographies of directly observed behavior. Five replications of multiple baselines were completed across a total of 16 participants with autism spectrum disorders. No consistent effects were observed across any group or within any individual participant, demonstrating that HBOT was not an effective treatment for the participants in this study. This study represents the first relatively large-scale controlled study evaluating the effects of HBOT at the level of the individual participant, on a wide array of behaviors.

引用

页码：575 / 588

页数：14

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