Effects of stimulant medication on divergent and convergent thinking tasks related to creativity in adults with attention-deficit hyperactivity disorder

被引:3
|
作者
McBride, Molly [1 ]
Appling, Carrina [2 ]
Ferguson, Bradley [2 ,3 ,4 ]
Gonzalez, Alyssia [5 ]
Schaeffer, Andrea [1 ]
Zand, Amanda [1 ]
Wang, David [6 ]
Sam, Alinna [1 ]
Hart, Eric [4 ]
Tosh, Aneesh [7 ]
Fontcha, Ivan [8 ]
Parmacek, Sophia [9 ]
Beversdorf, David [1 ,2 ,3 ,4 ,10 ,11 ,12 ]
机构
[1] Univ Missouri, Sch Med, Columbia, MO 65211 USA
[2] Univ Missouri, Interdisciplinary Neurosci Program, Columbia, MO 65211 USA
[3] Univ Missouri, Thompson Ctr Autism & Neurodev Disorder, Columbia, MO 65211 USA
[4] Univ Missouri, Dept Hlth Psychol, Columbia, MO 65211 USA
[5] Calif State Univ San Marcos, San Marcos, CA USA
[6] Emory Univ, Sch Med, Atlanta, GA USA
[7] Univ Missouri, Dept Child Hlth, Columbia, MO USA
[8] Univ Missouri, Dept Biol Sci, Columbia, MO USA
[9] Univ Missouri, Dept Psychol Sci, Columbia, MO USA
[10] Univ Missouri, Dept Radiol, Columbia, MO 65211 USA
[11] Univ Missouri, Dept Neurol, Columbia, MO 65211 USA
[12] Univ Missouri, Dept Psychol Sci, Columbia, MO 65211 USA
基金
美国国家科学基金会;
关键词
Stimulant medication; Attention-deficit hyperactivity disorder; Creativity; Dopamine; Norepinephrine; DEFICIT/HYPERACTIVITY DISORDER; INTEGRATIVE THEORY; ADHD; METHYLPHENIDATE; FLEXIBILITY; MODULATION; MECHANISMS; GENERATION; COGNITION; IDEA;
D O I
10.1007/s00213-021-05970-0
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Rationale Common pharmacological treatments for attention-deficit hyperactivity disorder (ADHD) are central nervous system stimulants acting as norepinephrine-dopamine reuptake inhibitors. The noradrenergic and dopaminergic systems have been shown to impact performance on tasks assessing creativity. Some previous studies suggest higher performance on creativity tasks in ADHD. Stimulant medication has been shown to differentially impact creativity in those without ADHD. However, the full range of effects of stimulant medication on creativity in those with ADHD is not known. Objectives This study examined the effects of stimulants on convergent and divergent tasks associated with creativity in adults with ADHD. Method Seventeen adults diagnosed with ADHD who were prescribed stimulant medication attended two counterbalanced sessions: one after taking their prescribed stimulant dose and one after the dose was withheld. Participants completed convergent problem-solving (anagrams, Compound Remote Associates) and divergent generative (letter/semantic fluency, Torrance Test for Creative Thinking (TTCT)-Verbal) tasks. Results There was a significant increase in words generated on the semantic fluency task for the stimulant session. Additionally, significant increases were found in the stimulant session for originality, flexibility, and fluency scores on the TTCT. Stimulant medication did not have an effect on any of the problem-solving tasks. Conclusions Stimulant medication enhanced verbal fluency in adults with ADHD but had no effect on convergent abilities. Furthermore, stimulants enhanced fluency, flexibility, and originality scores on the TTCT. Therefore, stimulants appear to have positive effects on divergent task performance in adults with ADHD, but not convergent tasks. This finding warrants further studies into the specific roles of norepinephrine and dopamine in this effect.
引用
收藏
页码:3533 / 3541
页数:9
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