A Review of Particle Therapy for Skull Base Tumors: Modern Considerations and Future Directions

被引：7
|
作者：
Hug, Eugen B. [1 ]
Pelak, Maciej [1 ]
Frank, Steven J. [2 ]
Fossati, Piero [1 ]
机构：
[1] MedAustron Ion Therapy Ctr, Wiener Neustadt, Austria
[2] MD Anderson Canc Ctr, Div Radiat Oncol, Houston, TX USA
来源：
INTERNATIONAL JOURNAL OF PARTICLE THERAPY | 2021年 / 8卷 / 01期
关键词：
skull base tumors; chordoma; carbon ion therapy; particle therapy; proton beam therapy; PROTON-BEAM THERAPY; FRACTIONATED STEREOTACTIC RADIOTHERAPY; RADIATION-THERAPY; VESTIBULAR SCHWANNOMA; CERVICAL-SPINE; CHORDOMAS; OUTCOMES; RADIOSURGERY; MANAGEMENT; SURGERY;
D O I：
10.14338/IJPT-20-00083
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Skull base tumors constitute one of the established indications for particle therapy, specifically proton therapy. However, a number of prognostic factors, practical clinical management issues, and the emerging role of carbon ion therapy remain subjects of active clinical investigation. This review summarizes these topics, assesses the present status, and reflects on future research directions focusing on the management of chordomas, one of the most aggressive skull base tumors. In addition, the role of particle therapy for benign tumors of the skull base, including pituitary adenoma and acoustic neuroma, is reviewed.
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页码：168 / 178
页数：11
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