Light-Controlled Nanocarriers for Drug Release

被引:1
|
作者
Gong Zhaocui [1 ]
Yin Chao [1 ]
Zhao Hui [1 ]
Lu Xiaomei [2 ]
Fan Quli [1 ]
Huang Wei [2 ]
机构
[1] Nanjing Univ Posts & Telecommun, Inst Adv Mat, Key Lab Organ Elect & Informat Displays, Nanjing 210023, Jiangsu, Peoples R China
[2] Nanjing Tech Univ, Inst Adv Mat, Nanjing 211816, Jiangsu, Peoples R China
基金
中国国家自然科学基金;
关键词
photosensitive nanocarriers; controlled drug release; cancer therapy; UP-CONVERSION NANOPARTICLES; PHOTOTHERMAL THERAPY; MAGNETIC NANOPARTICLES; MICELLES; PHOTO; COPOLYMER; DELIVERY; POLYMER; SPIROPYRAN; PHOTORELEASE;
D O I
10.7536/PC160211
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The study of light-responsive nanocarriers is becoming one of the hottest topics in biomedical field due to their precise control of drug release for cancer therapy in spatiotemporal level. This contribution systematically reviewed three mechanisms for controlled drug release of photosensitive nanocarriers, including ( 1) photoisomerization caused morphological transformation of nanocarriers, (2) photoreaction caused degradation of nanocarriers, and (3) photothermal caused disruption of nanocarriers. This review briefly introduced the three mechanisms and their corresponding photosensitive materials. In addition, the recent research developments and problems remained of photosensitive materials for drug delivery and controlled release were pointed out. This review also provided useful references for photosensitive nanocarriers in biological applications and the research prospects were further proposed.
引用
收藏
页码:1387 / 1396
页数:10
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