One-pot self-assembly of mesoporous silica nanoparticle-based pH-responsive anti-cancer nano drug delivery system

被引:35
|
作者
He, Qianjun [1 ]
Gao, Yu [2 ]
Zhang, Lingxia [1 ]
Bu, Wenbo [1 ]
Chen, Hangrong [1 ]
Li, Yaping [2 ]
Shi, Jianlin [1 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
关键词
SIZE; GLYCOPROTEIN; RELEASE; POLYMER; CELLS;
D O I
10.1039/c1jm13598h
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
A mesoporous silica nanoparticle (MSN)-based pH-responsive nano drug delivery system (hydrophobic drugs@micelles@MSNs) is constructed by a one-pot self-assembly strategy, exhibiting improved drug efficacy against both drug-resistant and drug-sensitive cancer cells.
引用
收藏
页码:15190 / 15192
页数:3
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