Fatal outcome of a hyperinfection syndrome despite successful eradication of Strongyloides with subcutaneous ivermectin

被引：38
|
作者：
Haubner, HP
Galle, J
Chiodini, PL
Rupp, J
Birke, R
Vollmer, E
Zabel, P
Lange, C
机构：
[1] Res Ctr Borstel, Med Clin, D-23845 Borstel, Germany
[2] Hosp Trop Dis, London NW1 0PE, England
[3] London Sch Hyg & Trop Med, London WC1, England
[4] Univ Hosp Lubeck, Dept Microbiol, Lubeck, Germany
来源：
INFECTION | 2005年 / 33卷 / 5-6期
关键词：
D O I：
10.1007/s15010-005-5060-x
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We report the case of a 77-year-old man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutaneous formulation of ivermectin. However, the patient subsequently died from acute respiratory distress syndrome (ARDS). Despite a high wormload in the stool and sputum of the patient and delayed infection control measures in the hospital, testing of the medical staff revealed a very Low risk of Strongyloides transmission among healthcare workers.
引用
收藏
页码：383 / 386
页数：4
相关论文
共 31 条
  • [1] Fatal Outcome of a Hyperinfection Syndrome despite Successful Eradication of Strongyloides with Subcutaneous Ivermectin
    H. P. Hauber
    J. Galle
    P. L. Chiodini
    J. Rupp
    R. Birke
    E. Vollmer
    P. Zabel
    C. Lange
    Infection, 2005, 33 : 383 - 386
  • [2] Subcutaneous ivermectin for the treatment of the hyperinfection syndrome by Strongyloides stercoralis
    Carolina Hennessey, Diana
    Andres Ballesteros, Oscar
    Javier Merchan, Diego
    Orlando Guevara, Freddy
    Fernando Severiche-Bueno, Diego
    BIOMEDICA, 2020, 40 (02): : 228 - 232
  • [3] Case Report: Failure of Subcutaneous Ivermectin in Treating Strongyloides Hyperinfection
    Leung, Victor
    Al-Rawahi, Ghada N.
    Grant, Jennifer
    Fleckenstein, Lawrence
    Bowie, William
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2008, 79 (06): : 853 - 855
  • [4] Subcutaneous ivermectin as a safe salvage therapy in Strongyloides stercoralis hyperinfection syndrome:: A case report
    Pacanowski, J
    Dos Santos, M
    Roux, A
    Le Maicnan, C
    Guillot, J
    Lavarde, V
    Cornet, M
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2005, 73 (01): : 122 - 124
  • [5] subcutaneous Ivermectin As Salvage Therapy In Strongyloides Hyperinfection In An Immunocompromised Host
    Lee, I. M.
    Raoof, N. D.
    Voigt, L. P.
    Halpern, N. A.
    Pastores, S. M.
    Kalanjeri, S.
    Brevetta, R. A.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2014, 189
  • [6] Fatal Strongyloides Hyperinfection Syndrome in an Immunocompromised Patient
    Pochineni, Vaishnavi
    Lal, Darshan
    Hasnayen, Shahed
    Restrepo, Erfidia
    AMERICAN JOURNAL OF CASE REPORTS, 2015, 16 : 603 - 605
  • [7] STRONGYLOIDES HYPERINFECTION SYNDROME: A RARE BUT COMMONLY FATAL CASE
    Amin, A.
    Thiruveety, P.
    Ibrahim, A.
    Elahee, M.
    Bautista, M.
    Boulos, A.
    CHEST, 2019, 155 (04) : 66A - 66A
  • [8] Case report:: Rectal adminstration of ivermectin to a patient with Strongyloides hyperinfection syndrome
    Tarr, PE
    Miele, PS
    Peregoy, KS
    Smith, MA
    Neva, FA
    Lucey, DR
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2003, 68 (04): : 453 - 455
  • [9] Strongyloides stercoralis Hyperinfection Syndrome as a Cause of Fatal Gastrointestinal Hemorrhage
    Rao, Shanti
    Tsai, Helen
    Tsai, Eugenia
    Nakanishi, Yukihiro
    Bulat, Robert
    ACG CASE REPORTS JOURNAL, 2019, 6 (03):
  • [10] Strongyloides stercoralis hyperinfection syndrome: A rare but fatal challenge in the ICU
    Lasa-Berasain, Pablo
    Orue, Andoni Presa
    Saenz, Veronica Diaz de Antonana
    Miro, Patricia Ares
    MEDICINA INTENSIVA, 2024, 48 (09) : 559 - 560
1234