Design, fabrication and testing of a micro-Venturi tube for fluid manipulation in a microfluidic system

被引：12
|
作者：
Yu, H. [1 ,2 ]
Li, D. [1 ]
Roberts, R. C. [2 ]
Xu, K. [1 ]
Tien, N. C. [2 ]
机构：
[1] Tianjin Univ, State Key Lab Precis Measuring Technol & Instrume, Tianjin 300072, Peoples R China
[2] Case Western Reserve Univ, Dept Elect Engn & Comp Sci, Cleveland, OH 44106 USA
来源：
JOURNAL OF MICROMECHANICS AND MICROENGINEERING | 2012年 / 22卷 / 03期
基金：
中国国家自然科学基金;
关键词：
PUMP;
D O I：
10.1088/0960-1317/22/3/035010
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
In this paper, a micro-Venturi tube fabricated with polydimethylsiloxane (PDMS) is studied for interstitial fluid (ISF) transdermal extraction and fluid manipulation in a microfluidic system toward the application of continuous glucose monitoring. The fabrication structure parameters of the PDMS Venturi tube were theoretically analyzed and experimentally validated against the output vacuum efficiency of the Venturi structure. The optimization methods of the Venturi structure were also discussed. In addition, an optimized micro-Venturi structure was proposed and fabricated. A vacuum pressure of less than 86 kPa had been achieved when an external pressure of 240 kPa was applied to this optimized Venturi tube. Both experimental and mathematical results demonstrate the potential applicability of the micro-Venturi tube in ISF transdermal extraction and fluid manipulation.
引用
收藏
页数：9
相关论文
共 50 条
  • [1] Hydrodynamics behaviour of a fluid flow in micro-venturi
    Maqableh, A. M.
    Ammourah, S. A.
    Khadrawi, A. F.
    Al-Nimr, M. A.
    Benim, A. C.
    CANADIAN JOURNAL OF PHYSICS, 2012, 90 (01) : 83 - 89
  • [2] Micro-Venturi injector: design, experimental and simulative examination
    Degenhardt, S.
    Cheriguen, Y.
    Geiling, T.
    Hoffmann, M.
    27TH MICROMECHANICS AND MICROSYSTEMS EUROPE WORKSHOP (MME 2016), 2016, 757
  • [3] A manufacturing technique for 3D polymer micro-venturi tube
    Chen, YT
    Kang, SW
    Chang, PF
    INTERNATIONAL JOURNAL OF MACHINE TOOLS & MANUFACTURE, 2003, 43 (04): : 421 - 424
  • [4] EVALUATION OF THE BUBBLE SIZE PRODUCED BY A POROUS TUBE AND A MICRO-VENTURI IN A MINI PILOT COLUMN FLOTATION
    Troian, A. S.
    Wiehe, C.
    Oliveira, C.
    Rodrigues, R. T.
    HOLOS, 2015, 31 (07) : 101 - 109
  • [5] Design and fabrication of microfluidic chip with micro/nano structures
    Chen, X.
    Cui, D. F.
    Zhang, L. L.
    2009 4TH IEEE INTERNATIONAL CONFERENCE ON NANO/MICRO ENGINEERED AND MOLECULAR SYSTEMS, VOLS 1 AND 2, 2009, : 98 - 101
  • [6] Micro-culture of single cell on microfluidic manipulation system
    Edagawa, Yoshikuni
    Arakawa, Takahiro
    Shoji, Shuichi
    Yamaguchi, Yoshinori
    NEUROSCIENCE RESEARCH, 2008, 61 : S278 - S278
  • [7] BLOOD MICROFLUIDIC SYSTEM FOR MAGNETIC FLUID TUBE WALL
    Liu, X. H.
    He, X. Y.
    Wang, W. L.
    Wu, Y.
    Han, X. B.
    Qi, J.
    Xu, B.
    MAGNETOHYDRODYNAMICS, 2024, 60 (1-2): : 87 - 99
  • [8] Design, fabrication and characterization of electrostatic micro actuators for microfluidic platforms
    Patrascu, M.
    Gonzalo-Ruiz, J.
    Goedbloed, M.
    Crego-Calama, M.
    Brongersma, S. H.
    EUROSENSORS XXV, 2011, 25
  • [9] Design, fabrication and testing of the micro punch for micro plastic tag
    Pang, Da-Chen
    Chang, Chao-Cheng
    4M/ICOMM 2009 - THE GLOBAL CONFERENCE ON MICRO MANUFACTURE, 2009, : 87 - 90
  • [10] Design and Fabrication of a PDMS-Based Manual Micro-Valve System for Microfluidic Applications
    Le, Tu N.
    Van-Anh Nguyen
    Bach, Giang L.
    Tran, Lam D.
    Cao, Ha H.
    ADVANCES IN POLYMER TECHNOLOGY, 2020, 2020
12345