Modifiable Risk-factors for Keratinocyte Cancers in Australia: A Case-control Study

被引：4

作者：

Serna-Higuita, Lina Maria ^{[1
]}

Harrison, Simone L. ^{[3
]}

Buttner, Petra ^{[3
]}

Glasby, Margaret ^{[3
]}

Raasch, Beverly A. ^{[3
]}

Iftner, Angelika ^{[2
]}

Garbe, Claus ^{[4
]}

Martus, Peter ^{[1
]}

Iftner, Thomas ^{[2
,3
]}

机构：

[1] Univ Hosp Tubingen, Dept Clin Epidemiol & Appl Biostat, Silcherstr 5, DE-72076 Tubingen, Germany

[2] Univ Hosp Tubingen, Inst Med Virol, Elfriede Aulhorn Str 6, DE-72076 Tubingen, Germany

[3] James Cook Univ, Coll Publ Hlth Med & Vet Sci, Skin Canc Res Unit, Townsville, Qld, Australia

[4] Univ Tubingen, Dept Dermatol, Div Dermatooncol, Tubingen, Germany

来源：

ACTA DERMATO-VENEREOLOGICA | 2019年 / 99卷 / 04期

关键词：

risk factor; keratinocyte cancer; sunlight; sunscreen; basal cell cancer; squamous cell cancer; NONMELANOMA SKIN-CANCER; SQUAMOUS-CELL CARCINOMA; TRANSPLANT RECIPIENTS; ULTRAVIOLET-RADIATION; SUN PROTECTION; BASAL-CELL; SUNSCREEN; TRENDS; PREVENTION; EXPOSURE;

D O I：

10.2340/00015555-3107

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Keratinocyte cancer is the most common malignancy in Caucasians. The aim of this study was to investigate risk-factors responsible for development of keratinocyte cancer in Australia. A case-control study was conducted, including 112 cases of squamous cell carcinoma (SCC), 95 cases of basal cell carcinoma (BCC) and 122 controls. Freckling during adolescence (SCC: odds ratio (OR) 1.04, p < 0.01; BCC: OR 1.05, p < 0.01), propensity to sunburn (SCC: OR 2.75, p = 0.01, BCC: OR 2.68 p = 0.01) and high cumulative sun-exposure (SCC: OR 2.43, p = 0.04; BCC: OR 2.36 p = 0.04) were independent risk-factors for both SCC and BCC. This study provides further evidence that a sun-sensitive phenotype and excessive sun-exposure during adulthood contribute to the risk of developing keratinocyte cancer. Wearing a hat, long-sleeved shirts, and sunscreen did not significantly reduce the risk of keratinocyte cancer in this study.

引用

页码：404 / 411

页数：8

共 50 条

[1] RISK-FACTORS FOR FIBROADENOMA - A CASE-CONTROL STUDY IN AUSTRALIA
YU, H
ROHAN, TE
COOK, MG
HOWE, GR
MILLER, AB
[J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 1992, 135 (03) : 247 - 258
[2] Influencing Risk Factors for Keratinocyte Cancer in Australia: Case-control Study
Higuita, Serna L. M.
Harrison, S.
Buttner, P.
Glasby, M.
Raasch, B.
McCutchan, C.
Iftner, A.
Garbe, C.
Martus, P.
Iftner, T.
[J]. JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2018, 16 : 72 - 72
[3] A CASE-CONTROL STUDY OF RISK-FACTORS FOR CRANIOSYNOSTOSIS
JOSHUA, S
ALDERMAN, B
FERGUSON, S
LAMMER, E
OUIMETTE, D
[J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 1986, 124 (03) : 532 - 533
[4] RISK-FACTORS FOR CRYPTORCHIDISM - A CASE-CONTROL STUDY
BEARD, C
MELTON, L
OFALLON, W
NOLLER, K
BENSON, R
[J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 1984, 120 (03) : 466 - 467
[5] CASE-CONTROL STUDY OF THE RISK-FACTORS FOR ECLAMPSIA
ABISAID, D
ANNEGERS, JF
COMBSCANTRELL, D
FRANKOWSKI, RF
WILLMORE, LJ
[J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 1995, 142 (04) : 437 - 441
[6] RISK-FACTORS FOR STRONGYLOIDIASIS - A CASE-CONTROL STUDY
DAVIDSON, RA
FLETCHER, RH
CHAPMAN, LE
[J]. ARCHIVES OF INTERNAL MEDICINE, 1984, 144 (02) : 321 - 324
[7] LEUKEMIA RISK-FACTORS, A CASE-CONTROL STUDY
LINOS, A
GRAY, J
ORVIS, A
KYLE, R
OFALLON, W
KURLAND, L
[J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 1979, 110 (03) : 358 - 359
[8] RISK-FACTORS FOR HEATSTROKE - A CASE-CONTROL STUDY
KILBOURNE, EM
CHOI, K
JONES, TS
THACKER, SB
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1982, 247 (24): : 3332 - 3336
[9] RISK-FACTORS ASSOCIATED TO HYPERURICEMIA - A CASE-CONTROL STUDY
RUIZ, MT
VIOQUE, J
NOLASCO, A
PASCUAL, E
[J]. BRITISH JOURNAL OF RHEUMATOLOGY, 1992, 31 : 222 - 222
[10] RISK-FACTORS FOR EPILEPSY - CASE-CONTROL STUDY IN NIGERIANS
OGUNNIYI, A
OSUNTOKUN, BO
BADEMOSI, O
ADEUJA, AOG
SCHOENBERG, BS
[J]. EPILEPSIA, 1987, 28 (03) : 280 - 285

← 1 2 3 4 5 →