One pot synthesis of aryl nitriles from aromatic aldehydes in a water environment

被引：7

作者：

Lin, Hongyan ^{[1
,2
]}

Zhou, Ziling ^{[1
,2
]}

Ma, Xiaopeng ^{[1
,2
]}

Chen, Qingqing ^{[1
,2
]}

Han, Hongwei ^{[1
,2
]}

Wang, Xiaoming ^{[1
,2
]}

Qi, Jinliang ^{[1
,2
]}

Yang, Yonghua ^{[1
,2
]}

机构：

[1] Nanjing Univ, State Key Lab Pharmaceut Biotechnol, Inst Plant Mol Biol, Sch Life Sci, Nanjing 210023, Peoples R China

[2] Nanjing Forestry Univ, Coinnovat Ctr Sustainable Forestry Southern China, Nanjing 210037, Peoples R China

来源：

RSC ADVANCES | 2021年 / 11卷 / 39期

基金：

中国国家自然科学基金;

关键词：

HIGHLY EFFICIENT; FORMIC-ACID; CONVERSION; DEHYDRATION; ALDOXIMES; HYDROXYLAMINE; CYANATION; CATALYST;

D O I：

10.1039/d1ra03559b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this study, we found a green method to obtain aryl nitriles from aromatic aldehyde in water. This simple process was modified from a conventional method. Compared with those approaches, we used water as the solvent instead of harmful chemical reagents. In this one-pot conversion, we got twenty-five aryl nitriles conveniently with pollution to the environment being minimized. Furthermore, we confirmed the reaction mechanism by capturing the intermediates, aldoximes.

引用

页码：24232 / 24237

页数：6

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