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Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi001-A) from a healthy male individual
被引:0
|作者:
Zhang, Jiwei
[1
]
Wei, Liting
[2
]
Wang, Rui
[4
]
Li, Xunhua
[3
]
Liu, Zhangsuo
[1
]
机构:
[1] Zhengzhou Univ, Affiliated Hosp 1, Zhengzhou 450052, Henan, Peoples R China
[2] Zhengzhou Univ, Dept Neurol, Luoyang Cent Hosp, Luoyang 467500, Henan, Peoples R China
[3] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Neurol, Guangzhou 510080, Guangdong, Peoples R China
[4] Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Guangzhou 510530, Guangdong, Peoples R China
基金:
中国博士后科学基金;
关键词:
D O I:
10.1016/j.scr.2020.101809
中图分类号:
Q813 [细胞工程];
学科分类号:
摘要:
Human iPSC Line, ZZUNEUi001-A, was generated from a healthy 38-year-old male individual, using non-integrating reprogramming methods. The resulting iPSCs were integration-free, expressed pluripotency stem cell markers, exhibited the potential for tri-lineage differentiation both in vitro and vivo, and maintained the normal karyotype. This cell line can be used as a control line for disease modelling.
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