Prevalence and Factors Associated with Prosthetic Joint Infections in Patients with Staphylococcus aureus Bacteraemia: A 7-Year Retrospective Study

被引:6
|
作者
Papadimitriou-Olivgeris, Matthaios [1 ,2 ,3 ]
Senn, Laurence [1 ,2 ,3 ]
Bertelli, Claire [2 ,4 ]
Grandbastien, Bruno [2 ,3 ]
Steinmetz, Sylvain [2 ,5 ]
Boillat-Blanco, Noemie [1 ,2 ]
机构
[1] Lausanne Univ Hosp, Infect Dis Serv, CH-1011 Lausanne, Switzerland
[2] Univ Lausanne, CH-1011 Lausanne, Switzerland
[3] Lausanne Univ Hosp, Infect Prevent & Control Unit, CH-1011 Lausanne, Switzerland
[4] Lausanne Univ Hosp, Inst Microbiol, CH-1011 Lausanne, Switzerland
[5] Lausanne Univ Hosp, Dept Orthopaed & Traumatol, CH-1011 Lausanne, Switzerland
来源
ANTIBIOTICS-BASEL | 2022年 / 11卷 / 10期
关键词
Staphylococcus aureus; bloodstream infection; prosthetic joint infection; arthroplasty; community-acquired infection; KNEE ARTHROPLASTY; HIP;
D O I
10.3390/antibiotics11101323
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Background: Staphylococcus aureus is the main cause of haematogenous prosthetic joint infections (PJI). We aimed to describe the prevalence and factors associated with PJI in patients with documented S. aureus bacteraemia. Methods: Adult patients with S. aureus bacteraemia and presence of prosthetic joint hospitalized in Lausanne University Hospital during a seven-year period (2015-2021) were included. Results: Among 135 patients with S. aureus bacteraemia and prosthetic joints, 38 (28%) had PJI. Multivariate analysis revealed that the presence of PJI was associated with knee arthroplasty (P 0.029; aOR 3.00, 95% CI 1.12-8.05), prior arthroplasty revision (P 0.034; aOR 3.59, 95% CI 1.10-11.74), community-acquired bacteraemia (P 0.005; aOR 4.74, 95% CI 1.61-14.01) and age < 70 years (P 0.007; aOR 9.39, 95% CI 1.84-47.85). Conclusions: PJI was common among patients with documented S. aureus bacteraemia. PJI was associated with characteristics of the prosthesis, such as prior arthroplasty revisions and knee prosthesis.
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页数:7
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