Metformin-associated Severe Lactic Acidosis in the Setting of Acute Kidney Injury

被引：2
|
作者：
Iftikhar, Hassaan [1 ]
Saleem, Maryam [2 ]
Kaji, Anand [3 ]
机构：
[1] Seton Hall Univ, St Francis Med Ctr, Internal Med, Trenton, NJ 08629 USA
[2] Waterbury Hosp & Hlth Ctr, Internal Med, Waterbury, CT USA
[3] St Francis Med, Internal Med, Trenton, NJ USA
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2019年 / 11卷 / 01期
关键词：
metformin; lactic acidosis; acute kidney injury; diabetes mellitus;
D O I：
10.7759/cureus.3897
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Metformin is a first-line biguanide agent for the treatment of diabetes mellitus. It has been known to be associated with lactic acidosis. This side effect especially worsens when being used with other medications affecting the kidney such as angiotensin-converting enzyme inhibitors (ACEi) and loop diuretics. This is a case of a 63-year-old male who suffered from metformin-induced lactic acidosis and underwent hemodialysis for treatment.
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页数：4
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