3rd International Meeting on Single Nucleotide Polymorphism and Complex Genome Analysis: SNPs: 'Some Notable Progress'

被引:4
|
作者
White, P. Scott [1 ,2 ]
Kwok, Pui-Yan [3 ]
Oefner, Peter [4 ]
Brookes, Anthony J. [5 ]
机构
[1] Los Alamos Natl Lab, Ctr Human Genome Studies, Los Alamos, NM USA
[2] Los Alamos Natl Lab, Biosci Div, Los Alamos, NM USA
[3] Washington Univ, Sch Med, Div Dermatol, St Louis, MO USA
[4] Stanford DNA Sequencing & Technol Ctr, Palo Alto, CA USA
[5] Karolinska Inst, Ctr Genom Res, Stockholm, Sweden
关键词
population genetics; variation; SNP genotyping; complex disease;
D O I
10.1038/sj.ejhg.5200616
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Fervent activities for the collection and exploitation of single nucleotide polymorphism (SNP) data continue, amid concerns about their real utility. The desire to understand complex disease aetiology remains a key driving force for this activity. Recent developments provided a level of cautious optimism not seen in previous International Meetings on Single Nucleotide Polymorphism and Complex Genome Analysis. The 3rd such meeting, held 8 - 11 September 2000 in Taos, New Mexico, covered research on technologies for SNP scoring, analytical tools for using SNPs to map disease genes, examples from researchers using SNPs for specific disease studies, and databases and tools for facilitating these activities. Studies of human history, and a range of studies upon model organisms were also represented. Whilst the transition from technology oriented work (methods, discovery, etc.) to successful biological application is occurring relatively slowly, a clear trend in this direction is now apparent, and it will surely gain momentum in future months and years. Many fundamental properties of SNPs remain unknown, and many other basic questions are still unanswered, but the field is moving forward on all necessary fronts, promising exciting advances just around the corner.
引用
收藏
页码:316 / 318
页数:3
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