Angiopoietin-like Protein 3 AND Cardiovascular Disease: A Mini Review

被引：0
|
作者：
Rai, Srinidhi [1 ]
机构：
[1] NITTE Deemed Univ, Dept Biochem, KS Hegde Med Acad KSHEMA, Mangalore 575018, India
来源：
JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL | 2021年 / 33卷 / 51A期
关键词：
Angiopoietin-like; 3; hyperlipidemia; T2DM; CVD; ANGPTL3; DEFICIENCY; REDUCING LIPIDS; CHOLESTEROL; EFFICACY; SAFETY;
D O I：
10.9734/JPRI/2021/v33i51A33481
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Objective of the review is to explore the role of angiopoietin like 3 protein (ANGPTL3) as a risk factor for cardiovascular disease. ANGPTL3 (human), one member of the angiopoietin-like protein (ANGPTL) family, has been identified as an important regulator of lipid metabolism. Dyslipidemia, characterized by elevation of plasma low density lipoprotein cholesterol (LDL-C), triglyceride (TG) and reduction of plasma high density lipoprotein cholesterol (HDL-C), has been verified as a causal risk factor for cardiovascular diseases (CVD), leading to a high mortality rate in general population. There may be an association between ANGPTL3, dyslipidemia, diabetes and cardiovascular risk.
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页码：169 / 172
页数：4
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