Akt1 and Akt3 exert opposing roles in the regulation of vascular tumor growth

被引：0
|
作者：
Phung, Thuy L. [1 ]
Xue, Qi [2 ]
Nhek, Sokha [2 ]
Gerald, Damien [2 ]
Perruzzi, Carole [2 ]
Ayyaswamy, Sriram [1 ]
Du, Wa [1 ]
Geeganage, Sandaruwan [3 ]
Benjamin, Laura [2 ]
机构：
[1] Texas Childrens Hosp, Houston, TX 77030 USA
[2] ImClone Syst, New York, NY USA
[3] Eli Lilly & Co, Indianapolis, IN 46285 USA
来源：
CANCER RESEARCH | 2014年 / 74卷 / 19期
关键词：
D O I：
10.1158/1538-7445.AM2014-3344
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3344
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Akt1 and Akt3 Exert Opposing Roles in the Regulation of Vascular Tumor Growth
    Phung, Thuy L.
    Du, Wa
    Xue, Qi
    Ayyaswamy, Sriram
    Gerald, Damien
    Antonello, Zeus
    Nhek, Sokha
    Perruzzi, Carole A.
    Acevedo, Isabel
    Ramanna-Valmiki, Rajesh
    Rodriguez-Waitkus, Paul
    Enayati, Ladan
    Hochman, Marcelo L.
    Lev, Dina
    Geeganage, Sandaruwan
    Benjamin, Laura E.
    CANCER RESEARCH, 2015, 75 (01) : 40 - 50
  • [2] Ligand-based modeling of Akt3 lead to potent dual Akt1/Akt3 inhibitor
    Al-Sha'er, Mahmoud A.
    Taha, Mutasem O.
    JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2018, 83 : 153 - 166
  • [3] Opposing roles of Akt1 and Akt2 in the Rac/PAK pathway
    Zhou, Guolei
    Bae, Sun Sik
    Bhatheja, Kanav
    Tucker, David F.
    Birnbaum, Morris J.
    Field, Jeffrey M.
    CANCER RESEARCH, 2006, 66 (08)
  • [4] Hepatic Stellate Cells Express AKT1 and AKT3 but Not AKT2.
    Kada, F.
    Rojkind, M.
    ENDOCRINE REVIEWS, 2010, 31 (03)
  • [5] Opposing roles for Akt1 and Akt2 in Rac/Pak signaling and cell migration
    Zhou, Guo-Lei
    Tucker, David F.
    Bae, Sun Sik
    Bhatheja, Kanav
    Birnbaum, Morris J.
    Field, Jeffrey
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (47) : 36443 - 36453
  • [6] Mutational analysis of AKT1, AKT2 and AKT3 genes in common human carcinomas
    Soung, Young Hwa
    Lee, Jong Woo
    Nam, Suk Woo
    Lee, Jung Young
    Yoo, Nam Jin
    Lee, Sug Hyung
    ONCOLOGY, 2006, 70 (04) : 285 - 289
  • [7] Subtle Impact of Akt1 and Akt3 on Exploratory Behavior in Gene Targeted Mice
    Leibrock, Christina
    Hierlmeier, Michael
    Lang, Undine E.
    Lang, Florian
    ZEITSCHRIFT FUR PSYCHOLOGIE-JOURNAL OF PSYCHOLOGY, 2015, 223 (03): : 173 - 180
  • [8] Akt1, Not Ak2 or Akt3, Regulates Oligodendrocyte Maturation In Vitro
    Minarcik, Jennifer A.
    Reid, Mary V.
    Birnbaum, Morris J.
    Po, Chen
    Grinspan, Judith B.
    Tennekoon, Gihan I.
    ANNALS OF NEUROLOGY, 2012, 72 : S117 - S118
  • [9] Akt1 and 2 mediate malignant progression in GBM, Akt3 has tumor suppressor-like function
    Joy, Anna M.
    Nakada, Mitsitoshi
    Seif-Naraghi, Sonya
    Tran, Nhan
    Nakada, Satoko
    Beaudry, Christian
    Fortin, Shannon
    Rennert, Jessica
    McDonough, Wendy
    Mariani, Luigi
    Zenklusen, John C.
    Fine, Howard A.
    Berens, Michael
    CANCER RESEARCH, 2006, 66 (08)
  • [10] Molecular alterations in AKT1, AKT2 and AKT3 detected in breast and prostatic cancer by FISH
    Kirkegaard, Tove
    Witton, Caroline J.
    Edwards, Joanne
    Nielsen, Kirsten Vang
    Jensen, Linda Boye
    Campbell, Fiona M.
    Cooke, Timothy G.
    Bartlett, John M. S.
    HISTOPATHOLOGY, 2010, 56 (02) : 203 - 211
12345