Recent developments in DNA electrophoretic separations

被引：41
|
作者：
Slater, GW
Kist, TBL
Ren, HJ
Drouin, G
机构：
[1] Univ Ottawa, Dept Phys, Ottawa, ON K1N 6N5, Canada
[2] Univ Fed Rio Grande do Sul, Inst Biociencias, Dept Biofis, BR-90049 Porto Alegre, RS, Brazil
[3] Univ Ottawa, Dept Biol, Ottawa, ON, Canada
来源：
ELECTROPHORESIS | 1998年 / 19卷 / 10期
关键词：
gel electrophoresis; DNA separation; DNA sequencing; free-flow electrophoresis; polymer solutions;
D O I：
10.1002/elps.1150191003
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
DNA electrophoresis is now a fairly mature technology. Nevertheless, as we approach the 21st century, new ideas are frequently suggested that could lead to a revolution for DNA sequencing and mapping. Here, we review some of the novel concepts that have been studied since ca. 1990. Our review focuses on new separation mechanisms, new sieving matrices and recent conceptual advances.
引用
收藏
页码：1525 / 1541
页数：17
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