Broadband Measurement Setup for Cell Electrorotation

被引：1

作者：

Barmutat, Pawel ^{[1
,2
]}

Markovic, Tomislav ^{[1
,3
]}

Campos, Camila Dalben Madeira ^{[1
,3
]}

Yadav, Rahul ^{[1
,3
]}

Ocket, Ilja ^{[3
]}

van Roy, Wim ^{[3
]}

Stakenborg, Tim ^{[3
]}

Lagae, Liesbet ^{[1
,3
]}

Genoe, Jan ^{[3
]}

Schreurs, Dominique ^{[1
]}

Liu, Chengxun ^{[3
]}

机构：

[1] Katholieke Univ Leuven, Dept Elect Engn, B-3001 Leuven, Belgium

[2] Warsaw Univ Technol, Inst Elect Syst, PL-00665 Warsaw, Poland

[3] Imec, Kapeldreef 75, B-3001 Heverlee, Belgium

来源：

2020 IEEE MTT-S INTERNATIONAL MICROWAVE BIOMEDICAL CONFERENCE (IMBIOC) | 2020年

关键词：

cell electrorotation; dielectric spectroscopy; single cell analysis; CYTOMETRY;

D O I：

10.1109/IMBIOC47321.2020.9385015

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

This work presents a broadband setup for single-cell electrorotation. It is capable of generating relatively high voltage in a continuous frequency band starting from 50 kHz up to 5 GHz. The setup shows very small phase and amplitude imbalance, which were found negligible as no decentric movement of the cell was observed. At least 9.6 V of peak-peak voltage at the single electrode was achieved with total harmonic distortion of less than 5%. The results obtained on lymphocytes follow the theoretical curves, and show that higher frequency of operation means higher sensitivity to the dielectric permittivity of the cell cytoplasm.

引用

页数：3

共 50 条

[1] Measurement Setup for the Analysis of Broadband Frequency-Modulated Signals
Zech, Christian
Baumann, Benjamin
Huelsmann, Axel
Kuehn, Lutta
Schlechtweg, Michael
Ambacher, Oliver
2016 46TH EUROPEAN MICROWAVE CONFERENCE (EUMC), 2016, : 385 - 388
[2] THE ELECTROROTATION OF AXISYMMETRICAL CELL
SOKIRKO, AV
BIOLOGICHESKIE MEMBRANY, 1992, 9 (04): : 432 - 439
[3] A broadband heterodyne measurement setup for active millimeter wave integrated antennas
Rasshofer, RH
Stiller, A
Thieme, MO
Schulz, H
Biebl, EM
1997 IEEE MTT-S INTERNATIONAL MICROWAVE SYMPOSIUM DIGEST, VOLS I-III: HIGH FREQUENCIES IN HIGH PLACES, 1997, : 1459 - 1462
[4] Measurement of dielectric properties of cells at single-cell resolution using electrorotation
Yuwen Li
Can Huang
Song-I Han
Arum Han
Biomedical Microdevices, 2022, 24
[5] Measurement of dielectric properties of cells at single-cell resolution using electrorotation
Li, Yuwen
Huang, Can
Han, Song-, I
Han, Arum
BIOMEDICAL MICRODEVICES, 2022, 24 (02)
[6] Short pulses and broadband measurement by autocorrelation with a sum-frequency generation setup
Glotin, F
Berset, JM
Jaroszynski, D
Marcouille, O
Ortega, JM
Peremans, A
Prazeres, R
Zheng, WQ
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1996, 375 (1-3): : 558 - 561
[7] Measurement of permittivity of biological particles based on electrorotation
School of Mechanical Engineering, Southeast University, Nanjing 211189, China
Dongnan Daxue Xuebao, 2007, 5 (861-866):
[8] A Broadband Test Setup for Differential Mode Measurement of Infrared Photodiodes in TO-8 Package
Abramowicz, Michal
Wiatr, Wojciech
2018 22ND INTERNATIONAL MICROWAVE AND RADAR CONFERENCE (MIKON 2018), 2018, : 294 - 297
[9] Thennal analysis of cell electrorotation chip
Xu, Guolin
Lee, Daniel
Vyshnavi, M.
Ying, Jackie Y.
BIOMEMS AND NANOTECHNOLOGY III, 2008, 6799
[10] The Search of Cell Positioning in Electrorotation measurements
Wang, Jun
Liao, Honghua
Chen, Jianjun
Luo, Lei
Zhou, Wenli
Yu, Jun
2009 3RD INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICAL ENGINEERING, VOLS 1-11, 2009, : 2849 - 2852

← 1 2 3 4 5 →