Water excitation MPRAGE MRI of VII and VIII cranial nerves

Objective: Our goal was to compare magnetization prepared rapid gradient echo-water excitation (MPRAGE-WE) with conventional spin echo (CSE) in the evaluation of the VII and VIII cranial nerves. Methods: One hundred three consecutive patients with symptoms referable to the VII/VIII nerves were studied with CSE T1 and MPRAGE-WE following intravenous gadolinium contrast agent, Each right and left nerve pair was independently evaluated for the presence of an enhancing mass and for visualization of the nerves. Results: On the CSE images, 26 definite and 2 possible lesions were identified, whereas 28 definite and 2 possible abnormalities were seen on the MPRAGE-WE. Four cases were better identified on the MPRAGE-WE and one better seen on the CSE. This difference was not statistically significant (p = 0.19), CSE demonstrated the nerves partially in 23 instances and completely in 6; MPRAGE-WE showed the nerves partially in 35 and completely in 73. This was highly significant (p < 0.001). Conclusion: With equivalent or slightly improved lesion detection and better visualization of the nerves, MPRAGE-WE may replace CSE in studying the VII/VIII nerves.