Localization of transferrin binding protein in relation to iron, ferritin, and transferrin receptors in the chicken cerebellum

被引:14
|
作者
Cho, SS
Shin, DH
Lee, KH
Hwang, DH
Chang, KY
机构
[1] Seoul Natl Univ, Coll Med, Dept Anat, Chongno Gu, Seoul 110799, South Korea
[2] Sungkyunkwan Univ, Coll Med, Dept Anat, Suwon 440746, South Korea
关键词
iron regulatory protein; Bergmann glia; Purkinje cell; immunohistochemistry; chicken brain;
D O I
10.1016/S0006-8993(98)00303-5
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We have demonstrated that transferrin binding protein (TfBP), ferritin, and iron, are specifically localized in Bergmann glia, while the transferrin receptor is confined to Purkinje cells in the chicken cerebellum. The results of this study suggest that Bergmann glia have previously undescribed functions related to iron regulation such as sequestration of iron and the maintenance of iron homeostasis in the cerebellum. (C) 1998 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:174 / 178
页数:5
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