Highly Substituted Cyclohexenes via Phosphine-Catalyzed [4+2] Annulation of Electron-deficient Dienes and Vinyl Ketones

被引：7
|
作者：
Chen, Peng [1 ]
Zhang, Junyou [1 ]
Zhang, Junliang [1 ]
机构：
[1] East China Normal Univ, Sch Chem & Mol Engn, Shanghai Key Lab Green Chem & Chem Proc, 3663 N Zhongshan Rd, Shanghai 200062, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2018年 / 360卷 / 04期
基金：
中国国家自然科学基金;
关键词：
4+2] annulation; electron-deficient diene; Vinyl Ketone; Phosphine catalyst; Cyclohexene; FUNCTIONALIZED CYCLOPENTENES; ENANTIOSELECTIVE SYNTHESIS; ACTIVATED ALKENES; ASYMMETRIC-SYNTHESIS; 3+2 CYCLOADDITIONS; CYCLIZATION; ALLENOATES; OLEFINS; ALLENES; DESIGN;
D O I：
10.1002/adsc.201701168
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A highly efficient phosphine-catalyzed [4+2] annulation of electron-deficient diene and alkyl vinyl ketone was developed for the first time, which provides an easy access to functionalized cyclohexenes. This method has the advantages of mild reaction conditions, widely functional group tolerance, high yields and transition metal free.
引用
收藏
页码：682 / 685
页数：4
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