Marijuana, Lower Urinary Tract Symptoms, and Pain in the Urologic Patient

被引：2
|
作者：
Pham, Minh N. [1 ]
Hudnall, Matthew T. [1 ]
Nadler, Robert B. [1 ]
机构：
[1] Northwestern Univ, Dept Urol, Feinberg Sch Med, 675 N St Clair St,Suite 20-1502, Chicago, IL 60611 USA
来源：
UROLOGY | 2020年 / 139卷
关键词：
RANDOMIZED-CONTROLLED-TRIAL; ADVANCED CANCER-PATIENTS; OROMUCOSAL SPRAY; DOUBLE-BLIND; MULTIPLE-SCLEROSIS; ADJUNCTIVE THERAPY; CANNABIS; BLADDER; RECEPTOR; OVERACTIVITY;
D O I：
10.1016/j.urology.2020.01.029
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
OBJECTIVE To describe marijuana's clinical role for urologic symptoms. METHODS Studies related to marijuana, voiding dysfunction, lower urinary tract symptoms (LUTS), and pain through January 2019 from PubMed were evaluated for relevance and quality. RESULTS Forty-eight studies were reviewed. Cannabinoids have mixed efficacy for neurogenic LUTS and little evidence for non-neurogenic LUTS, chronic non-cancer-related and perioperative pain. For cancer-related pain, high-level studies demonstrate cannabinoids are well-tolerated with unclear benefit. CONCLUSION Cannabinoids appear well-tolerated in the short-term, but their efficacy and long-term impact is unproven and unknown in urologic discomfort. Cannabinoids for urologic symptoms should be further explored with well-designed randomized controlled trials. (c) 2020 Elsevier Inc.
引用
收藏
页码：8 / 13
页数：6
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