Imaging in gastrointestinal stromal tumours: current status and future directions

被引：18
|
作者：
Kochhar, R. [1 ]
Manoharan, P. [1 ]
Leahy, M. [2 ]
Taylor, M. B. [1 ]
机构：
[1] Christie NHS Fdn Trust, Dept Radiol, Manchester M20 4BX, Lancs, England
[2] Christie NHS Fdn Trust, Dept Med Oncol, Manchester M20 4BX, Lancs, England
来源：
CLINICAL RADIOLOGY | 2010年 / 65卷 / 08期
关键词：
POSITRON-EMISSION-TOMOGRAPHY; IMATINIB MESYLATE; RESPONSE EVALUATION; PATHOLOGICAL CORRELATION; CLINICAL MANAGEMENT; SOLID TUMORS; FDG-PET; GIST; CT; RECURRENCE;
D O I：
10.1016/j.crad.2010.02.006
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Gastrointestinal stromal tumours (GISTs) have distinct biological and treatment-related features posing challenges for imaging. In this review the importance of imaging in different stages of patient management is discussed, emphasizing the unique characteristics of GISTs. Potential pitfalls of using the standard response criteria on conventional imaging have been highlighted. These include size measurements, which may not adequately reflect response rates, pseudo-progression, and spurious new lesions. Furthermore, the role of positron emission tomography/computed tomography (PET/CT) in early response evaluation and in the detection of both primary and acquired resistance is explored. The current role and future directions of use of both conventional and metabolic imaging in the management of GISTs are discussed. (C) 2010 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：584 / 592
页数：9
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