Palladium-Catalyzed Direct Hydroxymethylation of Aryl Halides and Inflates with Potassium Acetoxymethyltrifluoroborate

被引：34
|
作者：
Murai, Norio [1 ,2 ]
Yonaga, Masahiro [1 ,2 ]
Tanaka, Keigo [2 ]
机构：
[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan
[2] Eisai & Co Ltd, Discovery Res Labs, Tsukuba, Ibaraki 3002635, Japan
来源：
ORGANIC LETTERS | 2012年 / 14卷 / 05期
关键词：
CROSS-COUPLING REACTIONS; ORGANIC-SYNTHESIS; DERIVATIVES; INHIBITORS; CHLORIDES;
D O I：
10.1021/ol300149b
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Suzuki-Miyaura cross-coupling reactions of aryl halides and triflates with potassium acetoxymethyltrifluoroborate afforded the corresponding aryl and heteroaryl methanol products in moderate to excellent yields.
引用
收藏
页码：1278 / 1281
页数：4
相关论文
共 50 条
  • [1] Palladium-Catalyzed Direct Hydroxymethylation of Aryl Halides and Triflates with Potassium Acetoxymethyltrifluoroborate (vol 14, pg 1281, 2012)
    Murai, Norio
    Yonaga, Masahiro
    Tanaka, Keigo
    ORGANIC LETTERS, 2012, 14 (14) : 3812 - 3813
  • [2] A palladium-catalyzed reaction of aryl halides, potassium metabisulfite, and hydrazines
    Ye, Shengqing
    Wu, Jie
    CHEMICAL COMMUNICATIONS, 2012, 48 (80) : 10037 - 10039
  • [3] Palladium-catalyzed direct arylation of aryl methyl sulfoxides with aryl halides
    Jia, Tiezheng
    Peraza, Ana I. Bellomo
    Dreher, Spencer D.
    Walsh, Patrick J.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244
  • [4] Palladium-catalyzed Direct β-Arylation of Carbonyl Compounds with Aryl Halides
    Yada, Akira
    JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 2014, 72 (10) : 1156 - 1157
  • [5] Palladium-Catalyzed Direct Arylation of Methyl Sulfoxides with Aryl Halides
    Jia, Tiezheng
    Bellomo, Ana
    El Baina, Kawtar
    Dreher, Spencer D.
    Walsh, Patrick J.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (10) : 3740 - 3743
  • [6] Palladium-Catalyzed Aminosulfonylation of Aryl Halides
    Nguyen, Bao
    Emmett, Edward J.
    Willis, Michael C.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (46) : 16372 - 16373
  • [7] Palladium-Catalyzed Aminocarbonylation of Aryl Halides
    Afsina, Cheriya Mukkolakkal Abdulla
    Philip, Rose Mary
    Saranya, Padinjare Veetil
    Anilkumar, Gopinathan
    CURRENT ORGANIC SYNTHESIS, 2023, 20 (03) : 308 - 331
  • [8] Palladium-Catalyzed Decarboxylative Coupling of Potassium Nitrophenyl Acetates with Aryl Halides
    Shang, Rui
    Huang, Zheng
    Chu, Ling
    Fu, Yao
    Liu, Lei
    ORGANIC LETTERS, 2011, 13 (16) : 4240 - 4243
  • [9] Palladium-catalyzed benzylic direct arylation of benzyl sulfones with aryl halides
    Niwa, Takashi
    Yorimitsu, Hideki
    Oshima, Koichiro
    TETRAHEDRON, 2009, 65 (10) : 1971 - 1976
  • [10] A General and Practical Palladium-Catalyzed Direct α-Arylation of Amides with Aryl Halides
    Zheng, Bing
    Jia, Tiezheng
    Walsh, Patrick J.
    ADVANCED SYNTHESIS & CATALYSIS, 2014, 356 (01) : 165 - 178
12345