Effect of cigarette smoking on prepulse inhibition of the acoustic startle reflex in healthy male smokers

被引:106
|
作者
Kumari, V
Checkley, SA
Gray, JA
机构
[1] Institute of Psychiatry, University of London, London SE5 8AF, De Crespigny Park
基金
英国惠康基金;
关键词
prepulse inhibition; acoustic startle reflex; cigarette smoking; nicotine;
D O I
10.1007/s002130050109
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The present study investigated the effects of cigarette smoking on prepulse inhibition (PPI) of the acoustic startle reflex in healthy men. Cigarette smoking in a group of overnight smoking-deprived smokers increased PPI as compared to the smoking-deprived condition. This finding is consistent with previous animal studies showing that nicotine increases PPI of the acoustic startle reflex. In addition, cigarette smoking also reduced startle amplitude during the first 6-7 min of the post-smoking session.
引用
收藏
页码:54 / 60
页数:7
相关论文
共 50 条
  • [1] Effect of acute subcutaneous nicotine on prepulse inhibition of the acoustic startle reflex in healthy male non-smokers
    V. Kumari
    Paul A. Cotter
    Stuart A. Checkley
    Jeffrey A. Gray
    Psychopharmacology, 1997, 132 : 389 - 395
  • [2] Effect of acute subcutaneous nicotine on prepulse inhibition of the acoustic startle reflex in healthy male non-smokers
    Kumari, V
    Cotter, PA
    Checkley, SA
    Gray, JA
    PSYCHOPHARMACOLOGY, 1997, 132 (04) : 389 - 395
  • [3] Effect of detection on prepulse inhibition of the acoustic startle reflex
    Postma, P
    Gray, JA
    Nunn, JA
    Kumari, V
    JOURNAL OF PSYCHOPHYSIOLOGY, 2000, 14 (03) : 190 - 190
  • [4] Smoking withdrawal, nicotine dependence and prepulse inhibition of the acoustic startle reflex
    Veena Kumari
    Jeffrey A. Gray
    Psychopharmacology, 1999, 141 : 11 - 15
  • [5] Smoking withdrawal, nicotine dependence and prepulse inhibition of the acoustic startle reflex
    Kumari, V
    Gray, JA
    PSYCHOPHARMACOLOGY, 1999, 141 (01) : 11 - 15
  • [6] Influence of cigarette smoking on prepulse inhibition of the acoustic startle response in schizophrenia
    Kumari, V
    Soni, W
    Sharma, T
    HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL, 2001, 16 (04) : 321 - 326
  • [7] Caffeine and prepulse inhibition of the acoustic startle reflex
    M. A. Flaten
    Åke Elden
    Psychopharmacology, 1999, 147 : 322 - 330
  • [8] Caffeine and prepulse inhibition of the acoustic startle reflex
    Flaten, MA
    Elden, Å
    PSYCHOPHARMACOLOGY, 1999, 147 (03) : 322 - 330
  • [9] The effect of Imipramine on prepulse inhibition of the startle reflex in healthy subjects
    Hammer, TB
    Oranje, B
    Glenthoj, BY
    NORDIC JOURNAL OF PSYCHIATRY, 2005, 59 (05) : 411 - 411
  • [10] Neural correlates of enhanced prepulse inhibition of the startle reflex following nicotine in healthy male smokers and people with schizophrenia
    Postma, P
    Kumari, V
    Mehtrora, R
    Das, M
    Soni, W
    Simmons, A
    Wiliams, SCR
    Sharma, T
    Gray, JA
    JOURNAL OF PSYCHOPHARMACOLOGY, 2003, 17 (03) : A45 - A45