Statistical software for gene mapping by admixture linkage disequilibrium

被引:13
|
作者
Montana, Giovanni [1 ]
Hoggart, Clive [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Math, London SW7 2AZ, England
关键词
gene mapping; admixture linkage disequilibrium; hidden Markov models;
D O I
10.1093/bib/bbm035
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Admixture mapping is a statistical methodology that detects genetic variants in recently admixed populations that are responsible for ethnic differences in disease risk. Three software packages are now available for admixture mapping and we provide a brief overview of the statistical methods and other principal features they implement.
引用
收藏
页码:393 / 395
页数:3
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