Comparison of Treatment Rates of Depression After Stroke Versus Myocardial Infarction: A Systematic Review and Meta-Analysis of Observational Data

被引:31
|
作者
Ladwig, Simon [1 ,2 ]
Zhou, Zien [3 ,4 ]
Xu, Ying [4 ,5 ]
Wang, Xia [4 ]
Chow, Clara K. [6 ,7 ,8 ]
Werheid, Katja [2 ,9 ]
Hackett, Maree L. [4 ,10 ,11 ]
机构
[1] Univ Potsdam, Dept Psychol, Potsdam, Germany
[2] Ernst von Bergmann Hosp, Dept Neurol, Potsdam, Germany
[3] Shanghai Jiao Tong Univ, Sch Med, Ren Ji Hosp, Dept Radiol, Shanghai, Peoples R China
[4] Univ New South Wales, George Inst Global Hlth, Mental Hlth, Sydney, NSW, Australia
[5] Univ Sydney, Fac Med & Hlth, Sydney Sch Publ Hlth, Sydney, NSW, Australia
[6] Univ Sydney, Fac Med & Hlth, Westmead Appl Res Ctr, Sydney, NSW, Australia
[7] Westmead Hosp, Dept Cardiol, Sydney, NSW, Australia
[8] Univ New South Wales, George Inst Global Hlth, Cardiovasc Div, Sydney, NSW, Australia
[9] Humboldt Univ, Dept Psychol, Berlin, Germany
[10] Univ Sydney, Sydney Med Sch, Sydney, NSW, Australia
[11] Univ Cent Lancashire, Fac Hlth & Wellbeing, Preston, Lancs, England
基金
英国医学研究理事会;
关键词
depression; myocardial infarction; pharmacoepidemiology; stroke; treatment; CORONARY-HEART-DISEASE; POSTSTROKE DEPRESSION; LONG-TERM; CARDIOVASCULAR EVENTS; COGNITIVE IMPAIRMENT; FUNCTIONAL RECOVERY; SYMPTOMS; MORTALITY; CARE; REHABILITATION;
D O I
10.1097/PSY.0000000000000632
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective Depression after stroke and myocardial infarction (MI) is common but often assumed to be undertreated without reliable evidence being available. Thus, we aimed to determine treatment rates and investigate the application of guidelines in these conditions. Methods Databases MEDLINE, EMBASE, PsycInfo, Web of Science, CINAHL, and Scopus were systematically searched without language restriction from inception to June 30, 2017. Prospective observational studies with consecutive recruitment reporting any antidepressant treatment in adults with depression after stroke or MI were included. Random-effects models were used to calculate pooled estimates of treatment rates. Results Fifty-five studies reported 32 stroke cohorts (n = 8938; pooled frequency of depression = 34%, 95% confidence interval [CI] = 29%-38%) and 17 MI cohorts (n = 10,767; pooled frequency of depression = 24%, 95% CI = 20%-28%). In 29 stroke cohorts, 24% (95% CI = 20%-27%) of 2280 depressed people used antidepressant medication. In 15 MI cohorts, 14% (95% CI = 8%-19%) of 2381 depressed people used antidepressant medication indicating a lower treatment rate than in stroke. Two studies reported use of psychosocial interventions, indicating that less than 10% of participants were treated. Conclusions Despite the high frequency of depression after stroke and MI and the existence of efficacious treatment strategies, people often remain untreated. Innovative strategies are needed to increase the use of effective antidepressive interventions in patients with cardiovascular disease.
引用
收藏
页码:754 / 763
页数:10
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