Purpose of Review To identify the efficacy of radiofrequency ablation of pericranial nerves in treating headache. Recent Findings Recent studies by the same group showed promising results in treating headache using radiofrequency ablation. Pericranial nerves can be a therapeutic target for treating headache. Our results showed efficacy of radiofrequency ablation. More studies using other modalities as neuromodulation are needed and may show efficacy as well.