Antibiotic Resistance Patterns of Escherichia coli in Pediatric Urinary Tract Infections for the years 2001-2008

Although the changing patterns of antimicrobial resistance in urinary tract infection (UTI) are different in geographic regions, resistance of the mine isolates to commonly used antibiotics has increased significantly in many countries. We conducted a retrospective analysis to assess the change of antibiotic resistance of Escherichia con E. roll) in pediatric patients aged 0-15 years. Because the resistance rate of E. coli to ampicillin, co-trimoxazole, gentamicin. and first-generation cephalosporins were high, amoxicillin-clavulanic acid, second-generation cephalosporins, and amikacin could be reasonable alternative in the empirical treatment of the first UTI in children. Interestingly, there was a trend toward decreasing resistance of gentamicin cephalothin, and cefotaxime in our region. However it is unknown that decreased antimicrobial resistance was also occurred in other regions in our country, SO further epidemiologic data M several regions will be necessary to confirm our data.