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Shanghai Jiao Tong Univ, Renji Hosp,Minist Hlth, Sch Med,Key Lab Gastroenterol & Hepatol,State Key, Shanghai Inst Digest Dis,Div Gastroenterol & Hepa, 145 Middle Shandong Rd, Shanghai 200001, Peoples R China Shanghai Jiao Tong Univ, Renji Hosp,Minist Hlth, Sch Med,Key Lab Gastroenterol & Hepatol,State Key, Shanghai Inst Digest Dis,Div Gastroenterol & Hepa, 145 Middle Shandong Rd, Shanghai 200001, Peoples R China