Recent advances in asymmetric synthesis of pipecolic acid and derivatives - Review article

被引:84
|
作者
Kadouri-Puchot, C [1 ]
Comesse, S [1 ]
机构
[1] Univ Paris 06, CNRS, UMR 7611, Lab Chim Organ, Paris, France
关键词
pipecolic acid; pipecolic acid derivatives; amino acids; asymmetric syntheses; asymmetric catalysis;
D O I
10.1007/s00726-005-0193-x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This review covers the literature relating to asymmetric syntheses of pipecolic acid derivatives from 1997 to present. This review is organized according to the position and the degree of substitution of the piperidinic cycle. In a first section, syntheses of pipecolic acid itself are described. Then, successively, syntheses of C-3, C-4, C-5, C-6 substituted pipecolic acid derivatives are reported. Finally, syntheses of unsaturated pipecolic acid derivatives are presented before the last part devoted to the polysubstituted pipecolic acid derivatives.
引用
收藏
页码:101 / 130
页数:30
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