Acute retinal necrosis in children caused by herpes simplex virus

被引:29
|
作者
Tan, JCH
Byles, D
Stanford, MR
Frith, PA
Graham, EM
机构
[1] St Thomas Hosp, Med Eye Unit, London SE1 7EH, England
[2] Hosp Eye, Radcliffe Infirm, Oxford, England
来源
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | 2001年 / 21卷 / 04期
关键词
acute retinal necrosis; acyclovir; herpes simplex virus; necrotizing retinitis; polymerase chain reaction; vitreous aspirate;
D O I
10.1097/00006982-200108000-00008
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To report the diagnosis, management, and outcome of acute retinal necrosis syndrome in children. Method: Case series of three consecutive children aged 11 years and younger who were diagnosed with acute retinal necrosis. In addition to full ocular and systemic examinations, the children underwent vitreous biopsy (Patients 1 and 2) or aqueous tap (Patient 3) for polymerase chain reaction analysis. Results: All patients had unilateral retinitis that was associated with preexisting chorioretinal scars, and two patients (Patients 1 and 3) had concurrent extraocular central nervous system abnormalities. Intraocular herpes simplex virus was detected in all three children: Type 1 in Patient 1 and Type 2 in Patients 2 and 3. In addition, all three children had a history of extraocular herpes simplex virus infection. Conclusions: Retinitis associated with preexisting chorioretinal scars and detectable intraocular herpes simplex virus on polymerase chain reaction was common to all three children with acute retinal necrosis.
引用
收藏
页码:344 / 347
页数:4
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