Investigating the Correlation Between Serum Neurofilament Light Chain (sNfL) Concentration and Magnetic Resonance Imaging (MRI)-Outcomes in Patients With a First Clinical Demyelinating Event in the REFLEX Trial

被引：0
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作者：
Kuhle, Jens [1 ,2 ,3 ]
Leppert, David [1 ,2 ,3 ]
Comi, Giancarlo [4 ,5 ]
De Stefano, Nicola [6 ]
Kappos, Ludwig [1 ,2 ,3 ]
Freedman, Mark [7 ,8 ]
Seitzinger, Andrea [9 ]
Roy, Sanjeev [10 ]
机构：
[1] Neurol Clin & Policlin, Dept Med, Biomed Clin Res, Basel, Switzerland
[2] Univ Basel Hosp, Res Ctr Clin Neuroimmunol & Neurosci Basel RC2NB, Basel, Switzerland
[3] Univ Basel, Basel, Switzerland
[4] Univ Vita Salute San Raffaele, Dept Neurol, Osped San Raffaele, Milan, Italy
[5] Univ Vita Salute San Raffaele, Inst Expt Neurol, Osped San Raffaele, Milan, Italy
[6] Univ Siena, Dept Neurol & Behav Sci, Siena, Italy
[7] Univ Ottawa, Dept Med, Ottawa, ON, Canada
[8] Ottawa Hosp Res Inst, Ottawa, ON, Canada
[9] Merck KGaA, Darmstadt, Germany
[10] Merck, Div Merck KGaA, Aubonne, Switzerland
来源：
NEUROLOGY | 2021年 / 96卷 / 15期
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中图分类号：
R74 [神经病学与精神病学];
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摘要：
1116
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页数：4
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    Comi, G.
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    [J]. MULTIPLE SCLEROSIS JOURNAL, 2019, 25 : 785 - 786
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    Seitzinger, Andrea
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    [J]. THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS, 2024, 17
  • [3] Effect Of Interferon β-1a Treatment On Serum Neurofilament Light-chain Levels In Patients With A First Clinical Demyelinating Event In The REFLEX Trial
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    [J]. MULTIPLE SCLEROSIS JOURNAL, 2020, 26 (1_SUPPL) : 20 - 20
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    De Stefano, Nicola
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    Issard, Delphine
    [J]. NEUROLOGY, 2020, 94 (15)
  • [5] Effect of interferon beta-1a treatment on serum neurofilament light chain levels in patients with a1st clinical demyelinating event in the REFLEX trial
    Kuhle, J.
    Leppert, D.
    Comi, G.
    De Stefano, N.
    Kappos, L.
    Freedman, M.
    Roy, S.
    Issard, D.
    [J]. EUROPEAN JOURNAL OF NEUROLOGY, 2020, 27 : 340 - 341
  • [6] Cerebrospinal fluid neurofilament light chain protein correlates with magnetic resonance imaging markers of inflammation in patients with a first demyelinating episode
    Ungureanu, A.
    Piepgras, J.
    Papazoglou, S.
    Pfuhl, C.
    Oechtering, J.
    Behrens, J. Ruth
    Giess, R.
    Rasche, L.
    Pruess, H.
    Wuerfel, J.
    Zimmermann, H. G.
    Brandt, A.
    Bellmann-Strobl, J.
    Paul, F.
    Ruprecht, K.
    [J]. EUROPEAN JOURNAL OF NEUROLOGY, 2016, 23 : 826 - 826
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    [J]. MULTIPLE SCLEROSIS JOURNAL, 2020, 26 (3_SUPPL) : 133 - 134
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    Benova, B.
    Barro, C.
    Andelova, M.
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    Michalak, Z.
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    Kucerova, K.
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    Vaneckova, M.
    Kadrnozkova, L.
    Motyl, J.
    Havrdova, E.
    Kuhle, J.
    Horakova, D.
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