Doxorubicin-induced cardiomyopathy treated with carvedilol

被引：44
|
作者：
Fazio, S [1 ]
Palmieri, EA [1 ]
Ferravante, B [1 ]
Bone, F [1 ]
Biondi, B [1 ]
Sacca, L [1 ]
机构：
[1] Univ Naples Federico II, Div Med Interna 3, Sch Med, Dept Internal Med, I-80131 Naples, Italy
来源：
CLINICAL CARDIOLOGY | 1998年 / 21卷 / 10期
关键词：
doxorubicin; cardiomyopathy; carvedilol;
D O I：
10.1002/clc.4960211017
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Even today, heart failure due to doxorubicin-induced dilated cardiomyopathy seems to have a poor prognosis, as it is often irreversible and relatively unresponsive to standard medical treatment. This paper describes the first case of a patient complaining of severe symptoms of congestive heart failure due to doxorubicin-induced dilated cardiomyopathy unresponsive to standard medical treatment (digoxin, diuretics, and angiotensin-converting enzyme inhibitor), who showed complete clinical recovery and significant improvement of left ventricular dysfunction after carvedilol treatment. It also illustrates the possibility that carvedilol may be a first-choice drug for the treatment of this disease.
引用
收藏
页码：777 / 779
页数：3
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