SCY-078 antifungal activity in a murine model of invasive aspergillosis including azole-resistant strains

被引:0
|
作者
Barat, S. [1 ]
Borroto-Esoda, K. [1 ]
Angulo, D. [1 ]
Holden, K. [2 ]
Warn, P. [2 ]
机构
[1] Scynexis Inc, Jersey City, NJ USA
[2] Evotec UK, Manchester, Lancs, England
关键词
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
P313
引用
收藏
页码:209 / 209
页数:1
相关论文
共 50 条
  • [1] In vitro antifungal activity of SCY-078 against Candida parapsilosis, including azole and echinocandin-resistant strains
    Barat, S.
    Angulo, D.
    Borroto-Esoda, K.
    Ghannoum, M.
    MYCOSES, 2017, 60 : 209 - 210
  • [2] The effect of pH on the in vitro antifungal activity of SCY-078
    Larkin, Emily
    Hager, Christopher
    Long, Lisa
    Isham, Nancy
    Borroto-Esoda, Katyna
    Wring, Steve
    Angulo, David
    Ghannoum, Mahmoud
    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2017, 217 (06) : 736 - 736
  • [3] Evaluation of the Antifungal Activity of the Novel Oral Glucan Synthase Inhibitor SCY-078, Singly and in Combination, for the Treatment of Invasive Aspergillosis
    Ghannoum, M.
    Long, L.
    Larkin, E. L.
    Isham, N.
    Sherif, R.
    Borroto-Esoda, K.
    Barat, S.
    Angulo, D.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2018, 62 (06)
  • [4] Antifungal Activity of SCY-078 and Standard Antifungal Agents against 178 Clinical Isolates of Resistant and Susceptible Candida Species
    Schell, Wiley A.
    Jones, A. M.
    Borroto-Esoda, Katyna
    Alexander, Barbara D.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2017, 61 (11)
  • [5] Azole-Resistant Invasive Aspergillosis: Relationship to Agriculture
    Christen Rune Stensvold
    Lise Nistrup Jørgensen
    Maiken Cavling Arendrup
    Current Fungal Infection Reports, 2012, 6 (3) : 178 - 191
  • [6] Azole-Resistant Invasive Aspergillosis: Relationship to Agriculture
    Stensvold, Christen Rune
    Jorgensen, Lise Nistrup
    Arendrup, Maiken Cavling
    CURRENT FUNGAL INFECTION REPORTS, 2012, 6 (03) : 178 - 191
  • [7] Emergence of azole-resistant invasive aspergillosis in HSCT recipients in Germany
    Steinmann, J.
    Hamprecht, A.
    Vehreschild, M. J. G. T.
    Cornely, O. A.
    Buchheidt, D.
    Spiess, B.
    Koldehoff, M.
    Buer, J.
    Meis, J. F.
    Rath, P-M.
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2015, 70 (05) : 1522 - 1526
  • [8] Invasive pulmonary aspergillosis due to azole-resistant Aspergillus lentulus
    Tetsuka, Nobuyuki
    Yaguchi, Takashi
    Machida, Hiroyuki
    Ito, Shuichi
    Miyairi, Isao
    PEDIATRICS INTERNATIONAL, 2017, 59 (03) : 362 - 363
  • [9] Posaconazole Prophylaxis in Experimental Azole-Resistant Invasive Pulmonary Aspergillosis
    Seyedmousavi, Seyedmojtaba
    Mouton, Johan W.
    Melchers, Willem J. G.
    Verweij, Paul E.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2015, 59 (03) : 1487 - 1494
  • [10] Oral glucan synthase inhibitor SCY-078 is effective in an experimental murine model of invasive candidiasis caused by WT and echinocandin-resistant Candida glabrata
    Wiederhold, Nathan P.
    Najvar, Laura K.
    Jaramillo, Rosie
    Olivo, Marcos
    Pizzini, Jason
    Catano, Gabriel
    Patterson, Thomas F.
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2018, 73 (02) : 448 - 451