Acronyols A and B, new anti-inflammatory prenylated phloroglucinols from the fruits of Acronychia crassipetala

被引：5
|
作者：
Raju, Ritesh [1 ]
Mathew, Shintu [1 ]
Singh, Ahilya [1 ]
Reddell, Paul [2 ]
Munch, Gerald [1 ]
机构：
[1] Western Sydney Univ, Dept Pharmacol, Sydney, NSW, Australia
[2] QBiot Grp Ltd, Yungaburra, Qld, Australia
来源：
NATURAL PRODUCT RESEARCH | 2022年 / 36卷 / 17期
关键词：
Anti-inflammatory; phloroglucinols; Rutaceae; Acronychia crassipetala; TNF-alpha; ACETOPHENONE DERIVATIVES;
D O I：
10.1080/14786419.2021.1986711
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two new phloroglucinols, acronyols A (1) and B (2) along with the four known (3-6) pholoroglucinols were identified following anti-inflammatory activity guided fractionation from the fruits of Acronychia crassipetala (family Rutaceae). The pholoroglucinols (1-6) were evaluated for their inhibitory effects on NO production and downregulation of TNF-alpha in RAW 264.7 macrophage cell lines. [GRAPHICS] .
引用
收藏
页码：4364 / 4370
页数：7
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