Treatment of Acyclovir-Resistant Herpes Simplex Virus with Continuous Infusion of High-Dose Acyclovir in Hematopoietic Cell Transplant Patients

被引：27
|
作者：
Kim, Janet H. [2 ]
Schaenman, Joanna M. [2 ,3 ]
Ho, Dora Y. [1 ,2 ,3 ]
Brown, Janice M. Y. [1 ,2 ,3 ]
机构：
[1] Stanford Univ, Sch Med, Div Blood & Marrow Transplantat, Stanford, CA 94305 USA
[2] Stanford Univ, Sch Med, Dept Med, Stanford, CA 94305 USA
[3] Stanford Univ, Sch Med, Div Geog Med & Infect Dis, Stanford, CA 94305 USA
来源：
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION | 2011年 / 17卷 / 02期
关键词：
Acyclovir; Drug resistance; Immunocompromised host; Hematopoietic stem cell transplantation; ANTIVIRAL DRUGS; INFECTIONS; RECIPIENTS; THERAPY;
D O I：
10.1016/j.bbmt.2010.06.020
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Infection because of herpes simplex virus (HSV) that is resistant to acyclovir (ACV) poses treatment challenges in hematopoietic cell transplant (HCT) patients. We present a series of patients with ACV-resistant HSV following HCT who were successfully treated with continuous infusion high-dose ACV after failing standard treatment regimens for ACV-resistant HSV. Biol Blood Marrow Transplant 17: 259-264 (2011) (C) 2011 American Society for Blood and Marrow Transplantation
引用
收藏
页码：259 / 264
页数：6
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