Fenton chemistry in biology and medicine

被引：317
|
作者：
Prousek, Josef [1 ]
机构：
[1] Slovak Tech Univ, Fac Chem Food & Technol, Dept Environm Engn, SK-81237 Bratislava, Slovakia
来源：
PURE AND APPLIED CHEMISTRY | 2007年 / 79卷 / 12期
关键词：
Fenton reaction; reactive oxygen species; redox cycling; oxidative stress; free radicals; brown rot fungi; carcinogenesis; extracellular Fenton reaction;
D O I：
10.1351/pac200779122325
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Various aspects of the participation of Fenton chemistry in biology and medicine are reviewed. Accumulated evidence shows that both hydroxyl radical and ferryl [Fe(IV)=O](2+) can be formed under a variety of Fenton and Fenton-like reactions. Some examples of metal-independent hydroxyl radical production are included. Extracellular Fenton reaction is illustrated by the white rot and brown rot wood-decaying fungi. The natural and practical utilization of catechol-driven Fenton reaction is also presented.
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页码：2325 / 2338
页数：14
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