Fenton chemistry in biology and medicine

被引:317
|
作者
Prousek, Josef [1 ]
机构
[1] Slovak Tech Univ, Fac Chem Food & Technol, Dept Environm Engn, SK-81237 Bratislava, Slovakia
关键词
Fenton reaction; reactive oxygen species; redox cycling; oxidative stress; free radicals; brown rot fungi; carcinogenesis; extracellular Fenton reaction;
D O I
10.1351/pac200779122325
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Various aspects of the participation of Fenton chemistry in biology and medicine are reviewed. Accumulated evidence shows that both hydroxyl radical and ferryl [Fe(IV)=O](2+) can be formed under a variety of Fenton and Fenton-like reactions. Some examples of metal-independent hydroxyl radical production are included. Extracellular Fenton reaction is illustrated by the white rot and brown rot wood-decaying fungi. The natural and practical utilization of catechol-driven Fenton reaction is also presented.
引用
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页码:2325 / 2338
页数:14
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