The Stress Protein BAG3 Stabilizes Mcl-1 and Promotes Cancer Survival and Chemo-Resistance

被引：0
|
作者：
Boiani, Mariana [1 ]
Daniel, Cristina M. [1 ]
Liu, Xueyuan [2 ]
Hogarty, Michael D. [2 ]
Marnett, Lawrence J. [1 ]
机构：
[1] Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA
[2] Children Hosp Philadelphia, Div Oncol, Philadelphia, PA USA
来源：
FREE RADICAL BIOLOGY AND MEDICINE | 2011年 / 51卷
关键词：
D O I：
10.1016/j.freeradbiomed.2011.10.310
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：S120 / S120
页数：1
相关论文
共 50 条
  • [1] The Stress Protein BAG3 Stabilizes Mcl-1 Protein and Promotes Survival of Cancer Cells and Resistance to Antagonist ABT-737
    Boiani, Mariana
    Daniel, Cristina
    Liu, Xueyuan
    Hogarty, Michael D.
    Marnett, Lawrence J.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 288 (10) : 6980 - 6990
  • [2] Stabilization of Antiapoptotic Mcl-1 by the Hsp70 co-chaperone BAG3 in Cancer
    Boiani, Mariana
    Hogarty, Michael D.
    Marnett, Lawrence J.
    FREE RADICAL BIOLOGY AND MEDICINE, 2010, 49 : S56 - S56
  • [3] BAG3 upregulates Mcl-1 through downregulation of miR-29b to induce anticancer drug resistance in ovarian cancer
    Sugio, Asuka
    Iwasaki, Masahiro
    Habata, Shutaro
    Mariya, Tasuku
    Suzuki, Miwa
    Osogami, Hiroyuki
    Tamate, Masato
    Tanaka, Ryoichi
    Saito, Tsuyoshi
    GYNECOLOGIC ONCOLOGY, 2014, 134 (03) : 615 - 623
  • [4] Critical contribution of MCL-1 in EMT-associated chemo-resistance in A549 non-small cell lung cancer
    Toge, Masayoshi
    Yokoyama, Satoru
    Kato, Shinichiro
    Sakurai, Hiroaki
    Senda, Kazutaka
    Doki, Yoshinori
    Hayakawa, Yoshihiro
    Yoshimura, Naoki
    Saiki, Ikuo
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2015, 46 (04) : 1844 - 1848
  • [5] BAG3 directly stabilizes Hexokinase 2 mRNA and promotes aerobic glycolysis in pancreatic cancer cells
    An, Ming-Xin
    Li, Si
    Yao, Han-Bing
    Li, Chao
    Wang, Jia-Mei
    Sun, Jia
    Li, Xin-Yu
    Meng, Xiao-Na
    Wang, Hua-Qin
    JOURNAL OF CELL BIOLOGY, 2017, 216 (12): : 4091 - 4105
  • [6] Regulation of Mcl-1 stability: Impact on cancer cell survival and resistance radiotherapy
    Rudner, Justine
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2014, 34 : S14 - S14
  • [7] UCHL3 promotes pancreatic cancer progression and chemo-resistance through FOXM1 stabilization
    Song, Zhiwang
    Li, Junhe
    Zhang, Ling
    Deng, Jun
    Fang, Ziling
    Xiang, Xiaojun
    Xiong, Jianping
    AMERICAN JOURNAL OF CANCER RESEARCH, 2019, 9 (09): : 1970 - 1981
  • [8] WT1 associated protein promotes metastasis and chemo-resistance to gemcitabine by stabilizing Fak mRNA in pancreatic cancer
    Li, Bing-Qi
    Liang, Zhi-Yong
    Seery, Samuel
    Liu, Qiao-Fei
    You, Lei
    Zhang, Tai-Ping
    Guo, Jun-Chao
    Zhao, Yu-Pei
    CANCER LETTERS, 2019, 451 : 48 - 57
  • [9] Regulation of Mcl-1 and its contribution to cell survival and drug resistance in breast cancer
    Booy, Evan
    Henson, Elizabeth
    Gibson, Spencer
    CANCER RESEARCH, 2009, 69
  • [10] NCK1-AS1 promotes NCK1 expression to facilitate tumorigenesis and chemo-resistance in ovarian cancer
    Chang, Hua
    Li, Baixue
    Zhang, Xue
    Meng, Xiangkai
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 522 (02) : 292 - 299
12345